ArticleDevelopmental neurobiology2019
Developmental Changes in Task-Induced Brain Deactivation in Humans Revealed by a Motor Task.
Article in Developmental neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Bimanual digit training improves right-hand dexterity in older adults by reactivating declined ipsilateral motor-cortical inhibition.Scientific reports · 2021Trial
- Neural Correlates of Motor Sequence Learning and Enhanced Offline Consolidation in 7-11-Year-Old Children.Human brain mapping · 2026Article
- Younger adult brain utilizes interhemispheric strategy via ipsilateral dorsal premotor cortex for fine control of dexterous finger movements, unlike the aging brain.Frontiers in aging neuroscience · 2025Article
- Blind individuals' enhanced ability to sense their own heartbeat is related to the thickness of their occipital cortex.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Motor Processing in Children With Cochlear Implants as Assessed by Functional Near-Infrared Spectroscopy.Perceptual and motor skills · 2024Article
- Theoretical proposal for restoration of hand motor function based on plasticity of motor-cortical interhemispheric interaction and its developmental rule.Frontiers in neurology · 2024Article
- The Domain-Specific Neural Basis of Auditory Statistical Learning in 5-7-Year-Old Children.Neurobiology of language (Cambridge, Mass.) · 2024Article
- Functional and Structural Properties of Interhemispheric Interaction between Bilateral Precentral Hand Motor Regions in a Top Wheelchair Racing Paralympian.Brain sciences · 2023Article
- Hyper-Adaptation in the Human Brain: Functional and Structural Changes in the Foot Section of the Primary Motor Cortex in a Top Wheelchair Racing Paralympian.Frontiers in systems neuroscience · 2022Article
- Existence of Interhemispheric Inhibition between Foot Sections of Human Primary Motor Cortices: Evidence from Negative Blood Oxygenation-Level Dependent Signal.Brain sciences · 2021Article
- Importance of the Primary Motor Cortex in Development of Human Hand/Finger Dexterity.Cerebral cortex communications · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Performing tasks activates relevant brain regions in adults while deactivating task-irrelevant regions. Here, using a well-controlled motor task, we explored how deactivation is shaped during typical human development and whether deactivation is related to task performance. Healthy right-handed children (8-11 years), adolescents (12-15 years), and young adults (20-24 years; 20 per group) underwent functional magnetic resonance imaging with their eyes closed while performing a repetitive button-press task with their right index finger in synchronization with a 1-Hz sound. Deactivation in the ipsilateral sensorimotor cortex (SM1), bilateral visual and auditory (cross-modal) areas, and bilateral default mode network (DMN) progressed with development. Specifically, ipsilateral SM1 and lateral occipital deactivation progressed prominently between childhood and adolescence, while medial occipital (including primary visual) and DMN deactivation progressed from adolescence to adulthood. In adults, greater cross-modal deactivation in the bilateral primary visual cortices was associated with higher button-press timing accuracy relative to the sound. The region-specific deactivation progression in a developmental period may underlie the gradual promotion of sensorimotor function segregation required in the task. Task-induced deactivation might have physiological significance regarding suppressed activity in task-irrelevant regions. Furthermore, cross-modal deactivation develops to benefit some aspects of task performance in adults.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.