ArticleIEEE transactions on biomedical circuits and systems2019
A mm-Sized Free-Floating Wirelessly Powered Implantable Optical Stimulation Device.
Article in IEEE transactions on biomedical circuits and systems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 65 citations in OpenAlex.
- Low-power analog and mixed-signal circuit techniques for next-generation miniature implantable neural interface systems.Biomedical engineering letters · 2026Review
- Distributed implantable microchips as wireless networks for neural sensing and stimulation.Frontiers in neuroscience · 2026Review
- NeuroFlare: An mmIEEE journal of solid-state circuits · 2025Article
- An Energy-Efficient and Artifact-Resilient ASIC for Simultaneous Neural Recording and Optogenetic Stimulation.IEEE transactions on biomedical circuits and systems · 2025Article
- Omnidirectional Wireless Power Transfer for Millimetric Magnetoelectric Biomedical Implants.IEEE journal of solid-state circuits · 2024Article
- A Design Review for Biomedical Wireless Power Transfer Systems with a Three-Coil Inductive Link through a Case Study for NICU Applications.Electronics · 2024Article
- A Wireless Battery-Free Implant With Optical Telemetry for In Vivo Cortical Stimulation.IEEE sensors letters · 2024Article
- Wireless closed-loop deep brain stimulation using microelectrode array probes.Journal of Zhejiang University. Science. B · 2024Review
- A Linear-Power-Regulated Wireless Power Transfer Method for Decreasing the Heat Dissipation of Fully Implantable Microsystems.Sensors (Basel, Switzerland) · 2022Article
- A Wearable Ultrasonic Neurostimulator - Part I: A 1D CMUT Phased Array System for Chronic Implantation in Small Animals.IEEE transactions on biomedical circuits and systems · 2021Article
- Wireless, battery-free, subdermally implantable platforms for transcranial and long-range optogenetics in freely moving animals.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- A Trimodal Wireless Implantable Neural Interface System-on-Chip.IEEE transactions on biomedical circuits and systems · 2020Article
- Recent Advances in Electrical Neural Interface Engineering: Minimal Invasiveness, Longevity, and Scalability.Neuron · 2020Review
- A Scalable and Low Stress Post-CMOS Processing Technique for Implantable Microsensors.Micromachines · 2020Article
- A mm-Sized Free-Floating Wireless Implantable Opto-Electro Stimulation Device.Micromachines · 2020Article
- A Dual-Output Reconfigurable Shared-Inductor Boost-Converter/Current-Mode Inductive Power Management ASIC With 750% Extended Output-Power Range, Adaptive Switching Control, and Voltage-Power Regulation.IEEE transactions on biomedical circuits and systems · 2019Article
- Wireless opto-electro neural interface for experiments with small freely behaving animals.Journal of neural engineering · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
This paper presents a mm-sized, free-floating, wirelessly powered, implantable optical stimulation (FF-WIOS) device for untethered optogenetic neuromodulation. A resonator-based three-coil inductive link creates a homogeneous magnetic field that continuously delivers sufficient power (>2.7 mW) at an optimal carrier frequency of 60 MHz to the FF-WIOS in the near field without surpassing the specific absorption rate limit, regardless of the position of the FF-WIOS in a large brain area. Forward data telemetry carries stimulation parameters by on-off-keying the power carrier at a data rate of 50 kb/s to selectively activate a 4 × 4 μLED array. Load-shift-keying back telemetry controls the wireless power transmission by reporting the FF-WIOS received power level in a closed-loop power control mechanism. LEDs typically require high instantaneous power to emit sufficient light for optical stimulation. Thus, a switched-capacitor-based stimulation architecture is used as an energy storage buffer with one off-chip capacitor to receive charge directly from the inductive link and deliver it to the selected μLED at the onset of stimulation. The FF-WIOS system-on-a-chip prototype, fabricated in a 0.35-μm standard CMOS process, charges a 10-μF capacitor up to 5 V with 37% efficiency and passes instantaneous current spikes up to 10 mA in the selected μLED, creating a bright exponentially decaying flash with minimal wasted power. An in vivo experiment was conducted to verify the efficacy of the FF-WIOS by observing light-evoked local field potentials and immunostained tissue response from the primary visual cortex (V1) of two anesthetized rats.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.