Evidence map›Paper›PMID 31135340›Full record

ArticleeLife2019

Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation.

Shengbo He, Martin Vickers, Jingyi Zhang, Xiaoqi Feng

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 88 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Shengbo HeDepartment of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom.ORCID 0000-0003-3773-9995
Martin VickersDepartment of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom.
Jingyi ZhangDepartment of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom.
Xiaoqi FengDepartment of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom.ORCID 0000-0002-4008-1234
John Innes Centre · GB

Funding

Biotechnology and Biological Sciences Research Council BBL0250431H2020 European Research Council 804981 SexMeth
6 · The paper itself

Abstract

Transposable elements (TEs), the movement of which can damage the genome, are epigenetically silenced in eukaryotes. Intriguingly, TEs are activated in the sperm companion cell - vegetative cell (VC) - of the flowering plant

Indexed as

DNA DemethylationDNA Transposable ElementsArabidopsisArabidopsis ProteinsEpigenesis, GeneticGene Expression Regulation, PlantHeterochromatinHistonesN-Glycosyl HydrolasesPlant CellsTrans-ActivatorsArabidopsis ProteinsDEMETER protein, ArabidopsisDNA Transposable ElementsHeterochromatinHistonesN-Glycosyl HydrolasesTrans-Activatorsactive DNA demethylationA. thalianachromosomesgene expressionheterochromatin condensationhistone H1plant biologysex cellstransposable elements

Identifiers

PMID31135340
PMCPMC6594752
OpenAlexW2898392666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.