Evidence map›Paper›PMID 31135102›Full record

ArticleObesity (Silver Spring, Md.)2019

Deconstructing Weight Management Interventions for Young Adults: Looking Inside the Black Box of the EARLY Consortium Trials.

Deborah F Tate, Leslie Lytle, Kristen Polzien, Molly Diamond, Kelsey R Leonard, John M Jakicic, Karen C Johnson, Christine M Olson, Kevin Patrick, Laura P Svetkey and 8 more

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Deborah F TateDepartments of Health Behavior and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-4915-5308
Leslie LytleDepartments of Health Behavior and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kristen PolzienLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Molly DiamondLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kelsey R LeonardDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
John M JakicicPhysical Activity and Weight Management Research Center, Department of Health and Physical Activity, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6800-9368
Karen C JohnsonDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.ORCID 0000-0002-3493-4077
Christine M OlsonDivision of Nutritional Sciences, Cornell University, Ithaca, New York, USA.
Kevin PatrickDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, California, USA.
Laura P SvetkeyDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Rena R WingDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, The Miriam Hospital/Weight Control and Diabetes Research Center, Providence, Rhode Island, USA.ORCID 0000-0002-0918-8252
Pao-Hwa LinDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Mathilda CodayDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Melissa N LaskaDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Gina MerchantDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, California, USA.
Sara J CzajaDepartment of Psychiatry and Behavioral Sciences, University of Miami, Miami, Florida, USA.
Richard SchulzDepartment of Psychology and University Center for Social and Urban Research, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Steven H BelleEpidemiology & Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Venkata Saroja Voruganti · 1999 to 2026
$31.6M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Prevention of Weight Gain in Young AdultsU01HL090864 · NHLBI · MIRIAM HOSPITAL · PI WING, RENA R · 2009 to 2014
$5.8M
Enhanced Behavioral Intervention to Improve Long-Term Weight Loss in Young AdultsU01HL096770 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELLE, STEVEN H., JAKICIC, JOHN M · 2009 to 2014
$5.4M
Cell phone Intervention Trail for Young Adults (CITY)U01HL096720 · NHLBI · DUKE UNIVERSITY · PI SVETKEY, LAURA P · 2009 to 2013
$5.1M
SMART: A Social and Mobile Weight Control Program for Young AdultsU01HL096715 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PATRICK, KEVIN · 2009 to 2013
$4.9M
Electronically-Mediated Weight Interventions for Pregnant and Postpartum WomenU01HL096760 · NHLBI · CORNELL UNIVERSITY · PI FERNANDEZ, ISABEL DIANA, OLSON, CHRISTINE MARIE · 2009 to 2013
$4.5M
Targeted Approaches to Weight Control for Young Adults Grant with RCU ProposalU01HL096628 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JOHNSON, KAREN C · 2009 to 2013
$4.3M
Evaluating Innovative Weight Reduction Strategies for College StudentsU01HL096767 · NHLBI · UNIVERSITY OF MINNESOTA · PI LASKA, MELISSA N. · 2009 to 2013
$4.0M
Cross-study analysis of coordinated randomized clinical trials for weight managemR01HL122144 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELLE, STEVEN H., TATE, DEBORAH F. · 2015 to 2018
$3.0M
Prevention of Weight Gain in Young AdultsU01HL090875 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ESPELAND, MARK ANDREW · 2009 to 2014
$2.0M
NHLBI NIH HHS R01 HL122144NHLBI NIH HHS U01 HL090864NHLBI NIH HHS U01 HL090875NHLBI NIH HHS U01 HL096628NHLBI NIH HHS U01 HL096715NHLBI NIH HHS U01 HL096720NHLBI NIH HHS U01 HL096760NHLBI NIH HHS U01 HL096767NHLBI NIH HHS U01 HL096770NICHD NIH HHS R24 HD050924NIDDK NIH HHS P30 DK056350
6 · The paper itself

Abstract

objectiveThe goal of the present study was to deconstruct the 17 treatment arms used in the Early Adult Reduction of weight through LifestYle (EARLY) weight management trials.

methodsIntervention materials were coded to reflect behavioral domains and behavior change techniques (BCTs) within those domains planned for each treatment arm. The analytical hierarchy process was employed to determine an emphasis profile of domains in each intervention.

resultsThe intervention arms used BCTs from all of the 16 domains, with an average of 29.3 BCTs per intervention arm. All 12 of the interventions included BCTs from the six domains of Goals and Planning, Feedback and Monitoring, Social Support, Shaping Knowledge, Natural Consequences, and Comparison of Outcomes; 11 of the 12 interventions shared 15 BCTs in common across those six domains.

conclusionsWeight management interventions are complex. The shared set of BCTs used in the EARLY trials may represent a core intervention that could be studied to determine the required emphases of BCTs and whether additional BCTs add to or detract from efficacy. Deconstructing interventions will aid in reproducibility and understanding of active ingredients.

Indexed as

AdolescentAdultBehavior TherapyBody Weight MaintenanceFemaleHumansLife StyleMaleYoung Adult

Identifiers

PMID31135102
PMCPMC6749832

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.