Evidence map›Paper›PMID 31134755›Full record

ArticlePediatric blood & cancer2019

Adaptive functioning in pediatric brain tumor survivors: An examination of ethnicity and socioeconomic status.

Kimberly P Raghubar, Jessica Orobio, M Douglas Ris, Andrew M Heitzer, Alexandra Roth, Austin L Brown, M Fatih Okcu, Murali Chintagumpala, David R Grosshans, Arnold C Paulino and 2 more

Abstract read
In one paragraph

Article in Pediatric blood & cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Healthcare Self-Management, Executive Functioning, and Social Determinants of Health in Young Adults with Pediatric-Onset Disabilities: a Pilot Study.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
  2. Article
  3. Review
  4. Cognitive and Adaptive Functioning in Youth With Retinoblastoma: A Longitudinal Investigation Through 10 Years of Age.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kimberly P RaghubarDepartment of Pediatrics, Section of Psychology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-9332-181X
Jessica OrobioDepartment of Pediatrics, Section of Psychology, Baylor College of Medicine, Houston, Texas.
M Douglas RisDepartment of Pediatrics, Section of Psychology, Baylor College of Medicine, Houston, Texas.
Andrew M HeitzerDepartment of Pediatrics, Section of Psychology, Baylor College of Medicine, Houston, Texas.
Alexandra RothDepartment of Pediatrics, Section of Psychology, Baylor College of Medicine, Houston, Texas.
Austin L BrownDepartment of Pediatrics, Section of Hematology Oncology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0001-5802-5073
M Fatih OkcuDepartment of Pediatrics, Section of Hematology Oncology, Baylor College of Medicine, Houston, Texas.
Murali ChintagumpalaDepartment of Pediatrics, Section of Hematology Oncology, Baylor College of Medicine, Houston, Texas.
David R GrosshansDivision of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Arnold C PaulinoDivision of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.ORCID 0000-0002-0269-3045
Anita MahajanDivision of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Lisa S KahalleyDepartment of Pediatrics, Section of Psychology, Baylor College of Medicine, Houston, Texas.

Funding

Cognitive Change after Proton RT vs. Photon or Surgery for Pediatric Brain TumorR01CA187202 · NCI · BAYLOR COLLEGE OF MEDICINE · PI KAHALLEY, LISA SCHUM · 2014 to 2019
$2.9M
Neurocognitive Outcomes Following Proton Beam Radiation Therapy for Treatment ofK07CA157923 · NCI · BAYLOR COLLEGE OF MEDICINE · PI KAHALLEY, LISA SCHUM · 2011 to 2015
$743k
NCI NIH HHS K07 CA157923NCI NIH HHS R01 CA187202
6 · The paper itself

Abstract

backgroundSurvivors of pediatric brain tumor are at risk for adaptive difficulties. The present study examined adaptive functioning in a multiethnic sample of survivors accounting for socioeconomic status, and whether demographic, diagnostic, and/or treatment-related variables predict adaptive outcomes.

methodParticipants included a multiethnic sample of survivors (58 Caucasian, 34 Hispanic, and 22 other non-Caucasian; M age = 14.05 years, SD = 4.33) who were approximately seven years post-treatment. Parents rated adaptive functioning and provided demographic information. Diagnostic and treatment-related information was abstracted from the electronic medical record.

resultsParent ratings of adaptive functioning were similar across Caucasian, Hispanic, and other non-Caucasian survivors covarying for family income and primary caregiver education, both of which served as proxies for socioeconomic status. All ethnic groups were rated lower than the normative mean in overall adaptive functioning as well as the specific domains of conceptual, social, and practical skills. Demographic, diagnostic, and treatment-related variables were differentially associated with adaptive functioning in survivors of pediatric brain tumor, though socioeconomic status emerged as a strong significant predictor of adaptive functioning domains.

conclusionsAdaptive outcomes do not differ as a function of ethnicity after accounting for primary caregiver education and family income. Racial and ethnic minorities may be at increased risk for poorer outcomes given their overrepresentation at lower income levels. Assessing demographic and treatment-related variables early on may be helpful in identifying children likely to develop adaptive difficulties.

Indexed as

Cancer SurvivorsHispanic or LatinoSocial ClassWhite PeopleAdolescentAdultBrain NeoplasmsChildChild, PreschoolFemaleHumansMaleadaptive functioningbrain tumorethnicityradiationsocioeconomic status

Identifiers

PMID31134755
PMCPMC6730637

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.