Evidence map›Paper›PMID 31134696›Full record

ArticleClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2019

Human monoclonal antibodies to Ara h 2 inhibit allergen-induced, IgE-mediated cell activation.

Sumei Liao, Sarita U Patil, Wayne G Shreffler, Stephen C Dreskin, Xueni Chen

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sumei LiaoDivision of Allergy and Clinical Immunology, Departments of Medicine and Immunology, University of Colorado Denver, Aurora, Colorado.
Sarita U PatilCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, The Food Allergy Center, Boston, Massachusetts.
Wayne G ShrefflerCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, The Food Allergy Center, Boston, Massachusetts.
Stephen C DreskinDivision of Allergy and Clinical Immunology, Departments of Medicine and Immunology, University of Colorado Denver, Aurora, Colorado.
Xueni ChenDivision of Allergy and Clinical Immunology, Departments of Medicine and Immunology, University of Colorado Denver, Aurora, Colorado.ORCID 0000-0002-5181-4536
University of Colorado Denver · USHarvard University · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Ramnik J Xavier · 1991 to 2026
$35.3M
Tetramer CoreU19AI095261 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LUSTER, ANDREW D · 2011 to 2015
$10.8M
Redefining the Major Peanut AllergensR01AI052164 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DRESKIN, STEPHEN C · 2003 to 2011
$3.0M
Mapping the Critical Epitopes of Ara h 2 and Ara h 6R01AI099029 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DRESKIN, STEPHEN C · 2012 to 2015
$1.5M
Humoral mechanisms of tolerance in peanut oral immunotherapyK23AI121491 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI PATIL, SARITA U · 2016 to 2020
$975k
Designing a mimotope-based vaccine for peanut allergyR21AI137881 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CHEN, XUENI · 2019 to 2020
$428k
Elucidation of conformational epitopes of peanut allergens essential for allergic reactionsR21AI112792 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CHEN, XUENI · 2015 to 2016
$428k
Designing peptides to block Ara h 2 and Ara h 6 from binding to IgER21AI135397 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DRESKIN, STEPHEN C · 2019 to 2020
$427k
NCRR NIH HHS UL1 RR025780NIAID NIH HHS K23 AI121491NIAID NIH HHS R01 AI052164NIAID NIH HHS R01 AI099029NIAID NIH HHS R21 AI112792NIAID NIH HHS R21 AI135397NIAID NIH HHS R21 AI137881NIAID NIH HHS U19 AI095261NIDDK NIH HHS P30 DK043351
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

2S Albumins, PlantAntibodies, MonoclonalAntigens, PlantCell LineHumansImmunoglobulin EMast Cells2S Albumins, PlantAntibodies, MonoclonalAntigens, PlantAra h 2 allergen, Arachis hypogaeaImmunoglobulin E

Identifiers

PMID31134696
PMCPMC6682448
OpenAlexW2947166896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.