ArticleAnnals of the New York Academy of Sciences2019
Replacing iron-folic acid with multiple micronutrient supplements among pregnant women in Bangladesh and Burkina Faso: costs, impacts, and cost-effectiveness.
Article in Annals of the New York Academy of Sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Introduction of Multiple Micronutrient Supplementation to Antenatal Care in Bamako, Mali
Effectiveness of Multiple Micronutrient Supplementation Compared With Iron-Folic Acid Supplementation Among Pregnant Women in Bangladesh: an Experimental Protocol With 12-month Follow-up
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Antenatal multiple micronutrient supplements versus iron-folic acid supplements and birth outcomes: Analysis by gestational age assessment method.Maternal & child nutrition · 2023Pooled it
- Interventions to increase adherence to micronutrient supplementation during pregnancy: a systematic review.Annals of the New York Academy of Sciences · 2021Pooled it
- Self-management of iron and folic acid supplementation during pre-pregnancy, pregnancy and postnatal periods: a systematic review.BMJ global health · 2021Pooled it
- Impact of nutritional and multiple micronutrients supplementation to lactating mothers 6 months postpartum on the maternal and infant micronutrient status: a randomised controlled trial in Delhi, India.Public health nutrition · 2024Trial
- Cost-effectiveness and cost-utility of antenatal sexually transmitted infection screening to reduce preterm birth and low birthweight in South Africa.medRxiv : the preprint server for health sciences · 2026Article
- Qualitative Evaluation of the Pilot Introduction of Multiple Micronutrient Supplementation in Burkina Faso.Maternal & child nutrition · 2026Article
- Costs and benefits of replacing preventive antenatal iron and folic acid with multiple micronutrients in 25 low- and middle-income countries.BMJ global health · 2026Article
- Acceptability, Adherence, and Provision Through Antenatal Care: Evidence on Multiple Micronutrient Supplementation in Pakistan and Nigeria.Nutrients · 2026Article
- Prenatal multiple micronutrient supplementation in the Parepare district, Indonesia; population characteristics and intake adherence.BMC public health · 2025Article
- Cost-Effectiveness Analysis and Priority Setting in the Transition from Iron-Folic Acid (IFA) to Multiple Micronutrient Supplementation (MMS) for Pregnant Women in Indonesia.ClinicoEconomics and outcomes research : CEOR · 2025Article
- Cost-Effectiveness Analysis of Multiple Micronutrient Supplementation (MMS) Compared to Iron Folic Acid (IFA) in Pregnancy: A Systematic Review.International journal of women's health · 2025Review
- A qualitative assessment of barriers to iron and folic acid supplementation among pregnant women in Botswana.BMC public health · 2024Article
- Multiple micronutrient supplementation cost-benefit tool for informing maternal nutrition policy and investment decisions.Maternal & child nutrition · 2023Article
- Child Stunting Reduction in Aceh Province: Challenges and a Way Ahead.Maternal and child health journal · 2023Article
- Design, Methods, and Select Baseline Results from a School Nutrition Project for Adolescents in Bangladesh.Current developments in nutrition · 2023Article
- Vitamins and minerals, education, and self-care need during preconception to 1000 days of life in Southeast Asia: An expert panel opinion.SAGE open medicine · 2023Review
- Iron and Folic Acid Supplementation in Pregnancy: Findings from the Baseline Assessment of a Maternal Nutrition Service Programme in Bangladesh.Nutrients · 2022Article
- Multiple micronutrient supplements versus iron-folic acid supplements and maternal anemia outcomes: an iron dose analysis.Annals of the New York Academy of Sciences · 2022Article
- Article
- Can broad-spectrum multinutrients treat symptoms of antenatal depression and anxiety and improve infant development? Study protocol of a double blind, randomized, controlled trial (the 'NUTRIMUM' trial).BMC pregnancy and childbirth · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Consumption of multiple micronutrient supplements (MMS) during pregnancy offers additional benefits compared with iron-folic acid (IFA) supplementation, but the tablets are more expensive. We estimated the effects, costs, and cost-effectiveness of hypothetically replacing IFA supplements with MMS for 1 year in Bangladesh and Burkina Faso. Using baseline demographic characteristics from LiST and effect sizes from a meta-analysis, we estimated the marginal effects of replacing IFA with MMS on mortality, adverse birth outcomes, and disability-adjusted life years (DALYs) averted. We calculated the marginal tablet costs of completely replacing MMS with IFA (assuming 180 tablets per covered pregnancy). Replacing IFA with MMS could avert over 15,000 deaths and 30,000 cases of preterm birth annually in Bangladesh and over 5000 deaths and 5000 cases of preterm birth in Burkina Faso, assuming 100% coverage and adherence. We estimated the cost per death averted to be US$175-185 in Bangladesh and $112-125 in Burkina Faso. Cost per DALY averted ranged from $3 to $15, depending on the country and consideration of subgroup effects. Our estimates suggest that this policy change would cost-effectively save lives and reduce life-long disabilities. Improvements in program delivery and supplement adherence would be expected to improve the cost-effectiveness of replacing IFA with MMS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.