Evidence map›Paper›PMID 31134470›Full record

Trial reportEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2020

Assessment of the effects of a fluoride dentifrice and GC Tooth Mousse on early caries lesions in primary anterior teeth using quantitative light-induced fluorescence: a randomised clinical trial.

O B Al-Batayneh, E I Bani Hmood, S N Al-Khateeb

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. The Current Strategies in Controlling Oral Diseases by Herbal and Chemical Materials.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

O B Al-BataynehDepartment of Preventive Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, PO Box 3030, Irbid, 22110, Jordan. olabt@just.edu.jo.ORCID http://orcid.org/0000-0003-1670-497X
E I Bani HmoodDepartment of Preventive Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, PO Box 3030, Irbid, 22110, Jordan.
S N Al-KhateebDepartment of Preventive Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, PO Box 3030, Irbid, 22110, Jordan.

Funding

Deanship of Scientific Research/ Jordan University of Science and Technology, Irbid 22110, Jordan 522-2013Scientific Research Fund, Ministry of Higher Education and Research, Jordan SRF 2/3/2009
6 · The paper itself

Abstract

purposeTo compare the effects of a fluoride dentifrice alone, versus a topical CPP-ACP crème used as a dentifrice, versus the combination of both agents (fluoride dentifrice followed by CPP-ACP crème) on early caries lesions (ECL) in primary anterior teeth of children over a 6-month period.

methodsIn this single blinded randomised clinical trial, children (n = 114, aged 4-5 years) with high caries risk and who had at least one ECL (ICDAS 2) on their primary anterior teeth were allocated to three groups. Subjects used different agents twice daily: fluoride dentifrice (500 ppm F, n = 42), CPP-ACP crème (10% w/v, n = 35), and the fluoride dentifrice followed by CPP-ACP crème (n = 37). Changes in lesions were tracked using QLF, comparing the baseline situation to 3 and 6 months of treatment.

resultsQLF changes consistent with mineral gain (∆F/fluorescence, lesion area) occurred in all three groups (baseline versus 3 months or 6 months, p ≤ 0.05 for all three groups). Differences between treatment groups were not statistically significant (p > 0.05).

conclusionThe topical CPP-ACP crème used alone gave effects similar to the fluoride dentifrice; however, the combination of the two did not give additive benefits over either agent used in isolation.

Indexed as

Dental CariesDentifricesCariostatic AgentsCaseinsChildChild, PreschoolFluoridesHumansMineralsQuantitative Light-Induced FluorescenceTooth RemineralizationCariostatic Agentscasein phosphopeptide-amorphous calcium phosphate nanocomplexCaseinsDentifricesFluoridesMineralsCasein phosphopeptide–amorphous calcium phosphate (CPP–ACP)Enamel caries lesionPrimary teethQuantitative light-induced fluorescence (QLF)Remineralisation

Identifiers

PMID31134470

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.