Evidence map›Paper›PMID 31134399›Full record

ArticleMikrochimica acta2019

An electrochemical troponin T aptasensor based on the use of a macroporous gold nanostructure.

Masoud Negahdary, Mostafa Behjati-Ardakani, Hossein Heli

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 46 citations in OpenAlex.

  1. Recent Advances in Aptamer-Based Applications in Cardiology.International journal of molecular sciences · 2026
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  13. Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Masoud NegahdaryYazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, 8916978477, Iran.
Mostafa Behjati-ArdakaniYazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, 8916978477, Iran.
Hossein HeliNanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, 71936355899, Iran. hheli7@yahoo.com.
Shahid Sadoughi University of Medical Sciences and Health Services · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A specific troponin T (TnT) binding aptamer was identified and immobilized on an electrodeposited macroporous gold nanostructure using poly(ethylene glycol) 600, to fabricate a novel and ultrasensitive TnT aptasensor. The transducer surface on the gold disk electrode was characterized by field emission scanning electron microscopy, and immobilization of the aptamer was monitored by open circuit potential measurements. Binding of TnT by the aptamer was monitored by differential pulse voltammetry using ferro/ferricyanide as the redox probe. The aptamer has a high affinity and specificity, and the electrode is sensitive and selective. Best operated at a working potential of 0.23 V (vs. Ag/AgCl), the electrode can detected TnT in the 0.05 to 5.0 ng mL

Indexed as

Acute coronary syndromesAptamerBiomarkerBiosensorMacroporeMyocardial infarctionMyocyte damageNanogoldPEG 600Redox marker

Identifiers

PMID31134399
OpenAlexW2947201818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.