Evidence map›Paper›PMID 31134371›Full record

ReviewSurgery today2020

Can rectal washout reduce anastomotic recurrence after anterior resection for rectal cancer? A review of the literature.

Kae Okoshi, Emiko Kono, Yasuko Tomizawa, Koichi Kinoshita

Abstract readReview
PubMed Publisher
In one paragraph

Review in Surgery today, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kae OkoshiDepartment of Surgery, The Japan Baptist Hospital, 47 Yamonomoto-cho, Kitashirakawa, Sakyo-ku, Kyoto, 606-8273, Japan. kae_md@kuhp.kyoto-u.ac.jp.
Emiko KonoDepartment of Surgery, Takatsuki Red Cross Hospital, Takatsuki, Japan.
Yasuko TomizawaDepartment of Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan.
Koichi KinoshitaDepartment of Surgery, The Japan Baptist Hospital, 47 Yamonomoto-cho, Kitashirakawa, Sakyo-ku, Kyoto, 606-8273, Japan.
Takatsuki Red Cross Hospital · JPTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Local recurrence rates of rectal cancer after anterior resection remain high, despite the continued efforts of surgeons to devise preventive measures. Anastomotic recurrence, a form of local recurrence, may be caused by the implantation of exfoliated cancer cells during resection, and rectal stump washout has been proposed as a way to reduce the risk of this occurring. In this review article, we explore the mechanism of anastomotic recurrence after low anterior resection for rectal cancer, and examine the history and effectiveness of rectal washout on reducing recurrence rates, with a focus on washout solutions, procedures, and devices. Despite the lack of evidence from randomized trials, rectal washout with normal saline or diluted iodine is performed almost routinely during low anterior resection. Clamping is usually done using cross-clamps, linear staplers, tourniquets, and other devices. Although viable cancer cells may be shed into the rectal lumen during surgical resection, their impact on anastomotic recurrence remains uncertain. However, washout poses little or no harm to patients, and appears acceptable as a routine procedure. Randomized controlled trials or large observational studies may help to clarify the best practices for rectal washout.

Indexed as

Neoplasm SeedingAnastomosis, SurgicalDigestive System Surgical ProceduresHumansNeoplasm Recurrence, LocalRectal NeoplasmsRectumTherapeutic IrrigationAnterior resectionExfoliated cancer cellsImplantationRectal cancerRectal washout

Identifiers

PMID31134371
OpenAlexW2947982615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.