Evidence map›Paper›PMID 31134290›Full record

ReviewRheumatology international2019

HLA-B27 spondyloarthritis and spotted fever rickettsiosis: case-based review.

Albert H Redford, Jaren R Trost, Wilmer L Sibbitt, Monthida Fangtham, N Suzanne Emil, Shalini Singh, Arthur D Bankhurst

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Rheumatology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Albert H RedfordDivision of Rheumatology, Department of Internal Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, 5th FL ACC, Albuquerque, NM, 87131, USA.ORCID http://orcid.org/0000-0001-7852-0565
Jaren R TrostDivision of Rheumatology, Department of Internal Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, 5th FL ACC, Albuquerque, NM, 87131, USA.ORCID http://orcid.org/0000-0002-2150-2822
Wilmer L SibbittDivision of Rheumatology, Department of Internal Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, 5th FL ACC, Albuquerque, NM, 87131, USA. WSibbitt@salud.unm.edu.ORCID http://orcid.org/0000-0001-5872-160X
Monthida FangthamDivision of Rheumatology, Department of Internal Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, 5th FL ACC, Albuquerque, NM, 87131, USA.ORCID http://orcid.org/0000-0002-4591-4856
N Suzanne EmilDivision of Rheumatology, Department of Internal Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, 5th FL ACC, Albuquerque, NM, 87131, USA.ORCID http://orcid.org/0000-0002-2241-5464
Shalini SinghDivision of Rheumatology, Department of Internal Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, 5th FL ACC, Albuquerque, NM, 87131, USA.ORCID http://orcid.org/0000-0002-2724-0587
Arthur D BankhurstDivision of Rheumatology, Department of Internal Medicine, School of Medicine, University of New Mexico Health Sciences Center, MSC 10 5550, 5th FL ACC, Albuquerque, NM, 87131, USA.ORCID http://orcid.org/0000-0002-5286-7728
University of New Mexico · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rickettsia rickettsii, a tick borne disease, is the pathogen responsible for inducing Rocky Mountain Spotted Fever (RMSF), an illness that can progress to fulminant multiorgan failure and death. We present a case where R. rickettsii, acquired on a camping trip, precipitated a flare of peripheral arthritis and episcleritis in an HLA-B27 positive patient. Although Yersinia, Salmonella, Mycobacteria, Chlamydia, Shigella, Campylobacter, and Brucella have been previously associated with HLA-B27 spondyloarthritis, this unusual case demonstrates that obligate intracellular rickettsial organisms, and specifically, R. rickettsii, can also induce flares of HLA-B27 spondyloarthritis. Rickettsial infections in general can rapidly become fatal in both healthy and immunosuppressed patients, and thus, prompt diagnosis and therapy are required.

Indexed as

Immunocompromised HostAnti-Bacterial AgentsCertolizumab PegolDisease ProgressionDoxycyclineFemaleHLA-B27 AntigenHumansMiddle AgedRickettsia rickettsiiSpondylarthritisSpotted Fever Group RickettsiosisTreatment OutcomeTumor Necrosis Factor InhibitorsAnti-Bacterial AgentsCertolizumab PegolDoxycyclineHLA-B27 AntigenTumor Necrosis Factor InhibitorsHLA-B27InfectiousReactive arthritisRickettsiaSpondyloarthritis

Identifiers

PMID31134290
OpenAlexW2947762192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.