Evidence map›Paper›PMID 31134188›Full record

ArticleFrontiers in chemistry2019

Structural Changes in Polymeric Gel Scaffolds Around the Overlap Concentration.

Han Zhang, Matthew D Wehrman, Kelly M Schultz

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. High Entanglement in Hydrogels: From Polymer Physics to Robust Mechanics.Polymer science & technology (Washington, D.C.) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Han ZhangDepartment of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA, United States.
Matthew D WehrmanDepartment of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA, United States.
Kelly M SchultzDepartment of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cross-linked polymeric gels are an important class of materials with applications that broadly range from synthetic wound healing scaffolds to materials used in enhanced oil recovery. To effectively design these materials for each unique applications a deeper understanding of the structure and rheological properties as a function of polymeric interactions is required. Increasing the concentration of polymer in each scaffold increases physical interactions between the molecules that can be reflected in the material structure. To characterize the structure and material properties, we use multiple particle tracking microrheology (MPT) to measure scaffolds during gelation. In MPT, fluorescently labeled probe particles are embedded in the material and the Brownian motion of these particles is captured using video microscopy. Particle motion is related to rheological properties using the Generalized Stokes-Einstein Relation. In this work, we characterize gelation of a photopolymerized scaffold composed of a poly(ethylene glycol) (PEG)-acrylate backbone and a PEG-dithiol cross-linker. Scaffolds with backbone concentrations below and above the overlap concentration, concentration where polymer pervaded volume begins to overlap, are characterized. Using time-cure superposition (TCS) we determine the critical relaxation exponent,

Indexed as

hydrogel scaffoldsmultiple particle tracking microrheologyphotopolymerizationpoly(ethylene glycol)time-cure superposition

Identifiers

PMID31134188
PMCPMC6517517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.