Evidence map›Paper›PMID 31134098›Full record

ReviewFrontiers in immunology2019

Behçet's Disease: An Overview of Etiopathogenesis.

Pietro Leccese, Erkan Alpsoy

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 4 pooled it
27.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 4 syntheses or guidelines pooled it, 227 citations in OpenAlex.

  1. Behçet's Disease: A Comprehensive Review on the Role ofInternational journal of molecular sciences · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Neuro-behcet's syndrome: epidemiology, mechanisms, and emerging strategies in diagnosis and treatment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  12. Article
  13. Elevated Peripheral CD161ACR open rheumatology · 2026
    Article
  14. Article
  15. Behçet-like Syndromes: A Comprehensive Review.Dermatopathology (Basel, Switzerland) · 2026
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Ocular Manifestations of Pediatric Behçet's Disease.Clinical medicine & research · 2025
    Review

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Pietro LecceseRheumatology Institute of Lucania (IRel) and the Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Potenza, Italy.
Erkan AlpsoyDepartment of Dermatology and Venereology, School of Medicine, Akdeniz University, Antalya, Turkey.
Akdeniz University · TROspedale Madonna Delle Grazie · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet's disease (BD) is a systemic inflammatory disease with a chronic, relapsing-remitting course of unknown etiology hallmarked predominantly by mucocutaneous lesions and ocular involvement. BD shares some common features with autoimmune and autoinflammatory diseases and spondyloarthropathies (MHC-I-opathies). It is related to more than one pathogenic pathway triggered by environmental factors such as infectious agents in genetically predisposed subjects. The interplay between genetic background and immune system is linked to the BD presentation. Genetic factors have been investigated extensively, and several recent genome-wide association studies have confirmed

Indexed as

AminopeptidasesBehcet SyndromeGenetic Predisposition to DiseaseGenetic VariationHLA-B AntigensHumansInterleukin-17Minor Histocompatibility AntigensNeutrophil InfiltrationNeutrophilsStreptococcusStreptococcus sanguisTh17 CellsTh1 CellsT-Lymphocytes, RegulatoryAminopeptidasesERAP1 protein, humanHLA-B AntigensIL17A protein, humanInterleukin-17Minor Histocompatibility AntigensBehçet's diseaseetiologygeneticsimmunologyinfectious agents

Identifiers

PMID31134098
PMCPMC6523006
OpenAlexW2944777679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.