Evidence map›Paper›PMID 31134068›Full record

ArticleFrontiers in immunology2019

Probiotics May Have Beneficial Effects in Parkinson's Disease:

Luca Magistrelli, Angela Amoruso, Luca Mogna, Teresa Graziano, Roberto Cantello, Marco Pane, Cristoforo Comi

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05173701 (Effects of Probiotics on Peripheral Immunity in Parkinson's Disease), which is not on this map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05173701 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effects of Probiotics on Peripheral Immunity in Parkinson's Disease

TypeinterventionalSponsorFranca MarinoRan2021 to 2023Enrolled88ConditionsParkinson's DiseaseArmsProbiotics, Placebo
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 143 citations in OpenAlex.

  1. Trial
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  4. The effects ofIBRO neuroscience reports · 2026
    Article
  5. Review
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  7. Article
  8. Gut-Brain Signaling in Parkinson's Disease: A Narrative Review.International journal of molecular sciences · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
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  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Luca MagistrelliPhD Program in Clinical and Experimental Medicine and Medical Humanities, University of Insubria, Varese, Italy.
Angela AmorusoBiolab Research Srl, Research and Development, Novara, Italy.
Luca MognaBiolab Research Srl, Research and Development, Novara, Italy.
Teresa GrazianoBiolab Research Srl, Research and Development, Novara, Italy.
Roberto CantelloNeurology Unit, Department of Translational Medicine, Interdisciplinary Research Centre of Autoimmune Diseases, Movement Disorders Centre, University of Piemonte Orientale, Novara, Italy.
Marco PaneBiolab Research Srl, Research and Development, Novara, Italy.
Cristoforo ComiNeurology Unit, Department of Translational Medicine, Interdisciplinary Research Centre of Autoimmune Diseases, Movement Disorders Centre, University of Piemonte Orientale, Novara, Italy.
Probiotical (Italy) · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAntibiosisBifidobacteriumCaco-2 CellsCells, CulturedEscherichia coliFemaleHumansInterleukin-10Interleukin-17Interleukin-4Interleukin-6Klebsiella pneumoniaeLactobacillusLeukocytes, MononuclearMaleInterleukin-10Interleukin-17Interleukin-4Interleukin-6Reactive Oxygen SpeciesTumor Necrosis Factor-alphacytokinesneuroinflammationoxidative stressParkinson's disease (PD)probiotic

Identifiers

PMID31134068
PMCPMC6513970
OpenAlexW2944192801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.