ReviewFrontiers in endocrinology2019
Tanycyte Gene Expression Dynamics in the Regulation of Energy Homeostasis.
Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 55 citations in OpenAlex.
- The role of tanycytes in the regulation of energy balance.Reviews in endocrine & metabolic disorders · 2026Review
- Review
- Cellular expression domains of type 3 deiodinase in the meninges, choroid plexus, tanycytes and barrier tissues of the brain.Frontiers in endocrinology · 2026Article
- The unanticipated role of the glial-associated glucose-6-phosphatase system in brain homeostasis.iScience · 2025Review
- Perspective for Modulation of Hypothalamic Neurogenesis: Integrating Anatomical Insights with Exercise and Dietary Interventions.International journal of molecular sciences · 2025Review
- Article
- Tanycytes from a bird's eye view: gene expression profiling of the tanycytic region under different seasonal states in the Svalbard ptarmigan.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2025Article
- ESCHR: a hyperparameter-randomized ensemble approach for robust clustering across diverse datasets.Genome biology · 2024Article
- Fasting induces metabolic switches and spatial redistributions of lipid processing and neuronal interactions in tanycytes.Nature communications · 2024Article
- A single-cell transcriptomic study of heterogeneity in human embryonic tanycytes.Scientific reports · 2024Article
- Cherries with Different Geographical Origins Regulate Neuroprotection in a Photoperiod-Dependent Manner in F344 Rats.Antioxidants (Basel, Switzerland) · 2024Article
- The influence of extended fasting on thyroid hormone: local and differentiated regulatory mechanisms.Frontiers in endocrinology · 2024Review
- The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis.The Journal of clinical investigation · 2023Article
- The role of supporting and disruptive mechanisms of FT3 homeostasis in regulating the hypothalamic-pituitary-thyroid axis.Therapeutic advances in endocrinology and metabolism · 2023Article
- GLUT2 expression by glial fibrillary acidic protein-positive tanycytes is required for promoting feeding-response to fasting.Scientific reports · 2022Article
- Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel.Communications biology · 2022Article
- Article
- Ontogeny of ependymoglial cells lining the third ventricle in mice.Frontiers in endocrinology · 2022Article
- Localization of fibroblast growth factor 23 protein in the rat hypothalamus.The European journal of neuroscience · 2021Article
- Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animal survival relies on a constant balance between energy supply and energy expenditure, which is controlled by several neuroendocrine functions that integrate metabolic information and adapt the response of the organism to physiological demands. Polarized ependymoglial cells lining the floor of the third ventricle and sending a single process within metabolic hypothalamic parenchyma, tanycytes are henceforth described as key components of the hypothalamic neural network controlling energy balance. Their strategic position and peculiar properties convey them diverse physiological functions ranging from blood/brain traffic controllers, metabolic modulators, and neural stem/progenitor cells. At the molecular level, these functions rely on an accurate regulation of gene expression. Indeed, tanycytes are characterized by their own molecular signature which is mostly associated to their diverse physiological functions, and the detection of variations in nutrient/hormone levels leads to an adequate modulation of genetic profile in order to ensure energy homeostasis. The aim of this review is to summarize recent knowledge on the nutritional control of tanycyte gene expression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.