Evidence map›Paper›PMID 31133810›Full record

ArticleFrontiers in cellular neuroscience2019

Spontaneous and Acetylcholine Evoked Calcium Transients in the Developing Mouse Utricle.

Holly A Holman, Lauren A Poppi, Micah Frerck, Richard D Rabbitt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Activation of GABAJournal of neurophysiology · 2020
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Holly A HolmanDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, United States.
Lauren A PoppiDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, United States.
Micah FrerckDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, United States.
Richard D RabbittDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, United States.
University of Utah · USHunter Medical Research Institute · AU

Funding

Biophysics and Biomechanics of the Semicircular CanalsR01DC006685 · NIDCD · UNIVERSITY OF UTAH · PI RABBITT, RICHARD D · 2005 to 2022
$6.8M
NIDCD NIH HHS R01 DC006685
6 · The paper itself

Abstract

Spontaneous calcium transients are present during early postnatal development in the mouse retina and cochlea, and play an important role in maturation of the sensory organs and neural circuits in the central nervous system (CNS). It is not known whether similar calcium transients occur during postnatal development in the vestibular sensory organs. Here we demonstrate spontaneous intracellular calcium transients in sensory hair cells (HCs) and supporting cells (SCs) in the murine utricular macula during the first two postnatal weeks. Calcium transients were monitored using a genetically encoded calcium indicator, GCaMP5G (G5), at 100 ms-frame

Indexed as

calciumGCaMP5Ghair cellneuronsupporting cellutricle

Identifiers

PMID31133810
PMCPMC6514437
OpenAlexW2943973242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.