Evidence map›Paper›PMID 31133713›Full record

ArticleScientific reports2019

Water-content related alterations in macro and micro scale tendon biomechanics.

Pamela F Lozano, Mario Scholze, Carsten Babian, Holger Scheidt, Franziska Vielmuth, Jens Waschke, Benjamin Ondruschka, Niels Hammer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Pamela F LozanoDepartment of Anatomy, University of Otago, Dunedin, New Zealand.
Mario ScholzeInstitute of Materials Science and Engineering, Chemnitz University of Technology, Chemnitz, Germany.
Carsten BabianInstitute of Legal Medicine, University of Leipzig, Leipzig, Germany.
Holger ScheidtInstitute for Medical Physics and Biophysics, Leipzig University, Leipzig, Germany.
Franziska VielmuthVegetative Anatomy, Faculty of Medicine, Institute of Anatomy, Ludwig Maximilian University of Munich, Munich, Germany.
Jens WaschkeVegetative Anatomy, Faculty of Medicine, Institute of Anatomy, Ludwig Maximilian University of Munich, Munich, Germany.
Benjamin OndruschkaInstitute of Legal Medicine, University of Leipzig, Leipzig, Germany.
Niels HammerDepartment of Anatomy, University of Otago, Dunedin, New Zealand. nlshammer@googlemail.com.
Leipzig University · DELudwig-Maximilians-Universität München · DEUniversity of Otago · NZChemnitz University of Technology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though it is known that the water content of biological soft tissues alters mechanical properties, little attempt has been made to adjust the tissue water content prior to biomechanical testing as part of standardization procedures. The objective of this study was to examine the effects of altered water content on the macro and micro scale mechanical tissues properties. Human iliotibial band samples were obtained during autopsies to osmotically adapt their water content. Macro mechanical tensile testing of the samples was conducted with digital image correlation, and micro mechanical tests using atomic force microscopy. Analyses were conducted for elastic moduli, tensile strength, and strain at maximum force, and correlations for water content, anthropometric data, and post-mortem interval. Different mechanical properties exist at different water concentrations. Correlations to anthropometric data are more likely to be found at water concentrations close to the native state. These data underline the need for adapting the water content of soft tissues for macro and micro biomechanical experiments to optimize their validity. The osmotic stress protocol provides a feasible and reliable standardization approach to adjust for water content-related differences induced by age at death, post-mortem interval and tissue processing time with known impact on the stress-strain properties.

Indexed as

AdolescentAdultAgedAged, 80 and overCadaverChildChild, PreschoolElastic ModulusFeasibility StudiesFemaleHumansMaleMaterials TestingMicroscopy, Atomic ForceMiddle AgedOsmosisWater

Identifiers

PMID31133713
PMCPMC6536550
OpenAlexW2946532758

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.