SynthesisBMC veterinary research2019
Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review.
Synthesis in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Shrubs and trees as natural insect protection for grazing animals in Switzerland and the alpine region: A systematic review of in vitro, in vivo and clinical trials.Medical and veterinary entomology · 2026Pooled it
- Review
- Topical cream with essential oils, zinc and salicylic acid reduces pruritus and skin lesion scores in pruritic dogs.Australian veterinary journal · 2026Article
- Comparative Efficacy of a Novel Topical Formulation with Antimicrobial Peptides and Encapsulated Plant Extracts Versus Conventional Therapies for Canine Otitis Externa.Pathogens (Basel, Switzerland) · 2025Article
- Efficacy Study of Propolis Eutectic Extract in Gel Formulations for the Treatment of Bacterial Skin Diseases in Dogs.Animals : an open access journal from MDPI · 2025Article
- In vitro characterization of potential botanicals to reduce infection and improve the rate of wound healing in humans and canines.BMC complementary medicine and therapies · 2025Article
- Phytotherapeutic Approaches in Canine Pediatrics.Veterinary sciences · 2024Review
- In Vitro Activity ofVeterinary sciences · 2024Article
- Evaluation of the Effectiveness of Medical-Grade Honey and Hypericum Perforatum Ointment on Second-Intention Healing of Full-Thickness Skin Wounds in Cats.Animals : an open access journal from MDPI · 2023Article
- Antimicrobial Activity ofVeterinary sciences · 2023Article
- In Vitro Antimicrobial Activity ofAnimals : an open access journal from MDPI · 2022Article
- Current Knowledge on Interactions of Plant Materials Traditionally Used in Skin Diseases in Poland and Ukraine with Human Skin Microbiota.International journal of molecular sciences · 2022Review
- Use of medicinal plants by veterinary practitioners in Spain: A cross-sectional survey.Frontiers in veterinary science · 2022Article
- In vitro and in vivo evaluation of a new phytotherapic blend to treat acute externa otitis in dogs.Journal of veterinary pharmacology and therapeutics · 2021Article
- Impact of Nutritional Supplementation on Canine Dermatological Disorders.Veterinary sciences · 2020Review
- Revealing the Hidden Details of Nanostructure in a Pharmaceutical Cream.Scientific reports · 2020Article
- Ethnoveterinary knowledge of farmers in bilingual regions of Switzerland - is there potential to extend veterinary options to reduce antimicrobial use?Journal of ethnopharmacology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMedicinal plants have been used traditionally since centuries for wound care and treatment of skin diseases both in human and animals. Skin diseases are one of the most common reasons for owners to take their dog to the veterinarian. The demands for treatment and prophylaxis of these diseases are broad. A wide range of bacteria including antibiotic-resistant bacteria can be involved, making the treatment challenging and bear an anthropo-zoonotic potential. The aim of this review is to systematically evaluate based on recent scientific literature, the potential of four medicinal plants to enrich the therapeutic options in pyoderma, canine atopic dermatitis, otitis externa, wounds and dermatophytosis in dogs.
resultsBased on four books and a survey among veterinarians specialized in phytotherapy, four medicinal plants were chosen as the subject of this systematic review: Calendula officinalis L. (Marigold), Hypericum perforatum L. agg. (St. John's Wort), Matricaria chamomilla L. (syn. Matricaria recutita L., Chamomile) and Salvia officinalis L. (Sage). According to the PRISMA statement through literature research on two online databases a total of 8295 publications was screened and narrowed down to a final 138 publications for which full-text documents were analyzed for its content resulting in a total of 145 references (21 clinical, 24 in vivo and 100 in vitro references).
conclusionsAll four plants were proven to have antibacterial and antifungal effects of a rather broad spectrum including antibiotic-resistant bacteria. This makes them an interesting new option for the treatment of pyoderma, otitis externa, infected wounds and dermatophytosis. Marigold, St. John's Wort and Chamomile showed wound-healing properties and are thus promising candidates in line to fill the therapeutic gap in canine wound-healing agents. St. John's Wort and Chamomile also showed anti-inflammatory and other beneficial effects on healthy skin. Due to the wide range of beneficial effects of these medicinal plants, they should be taken into account for the treatment of dermatologic diseases in dogs at least in future clinical research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.