Evidence map›Paper›PMID 31132989›Full record

ArticleBMC cardiovascular disorders2019

Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio in Chinese Han population from Chaoshan region in South China.

Lishan Wu, Shan Zou, Cantian Wang, Xuerui Tan, Min Yu

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Advances in laboratory medicine · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lishan WuDepartment of Cardiology, the First Affiliated Hospital, Shantou University Medical College, Shantou, 515041, Guangdong, China.
Shan ZouDepartment of Cardiology, the First Affiliated Hospital, Shantou University Medical College, Shantou, 515041, Guangdong, China.
Cantian WangDepartment of Cardiology, the First Affiliated Hospital, Shantou University Medical College, Shantou, 515041, Guangdong, China.
Xuerui TanDepartment of Cardiology, the First Affiliated Hospital, Shantou University Medical College, Shantou, 515041, Guangdong, China.
Min YuDepartment of Cardiology, the First Affiliated Hospital, Shantou University Medical College, Shantou, 515041, Guangdong, China. 717146@sina.com.ORCID 0000-0003-1135-5088

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are assumed to be prognostic factors in many diseases such as inflammatory diseases, cardiovascular diseases and cancer. However, NLR and PLR are race specific, it is important to determine the reference values of NLR and PLR in different races. The study aimed to investigate the reference range of NLR and PLR in Chinese Han population from Chaoshan region in South China.

methodsA retrospective study was conducted in the First Affiliated Hospital of Shantou University Medical College in South China. Five thousand healthy adults aged 20-69 years were included. NLR and PLR were determined.

resultsOf 5000 healthy adults, 2500 men and 2500 women were included. The mean NLR and PLR across all ages for men and women were 1.59 ± 0.59, 92.88 ± 28.70, 1.62 ± 0.64 and 108.02 ± 32.99, respectively. The 95% reference range of NLR in normal male and female are 0.43~2.75 and 0.37~2.87, PLR are 36.63~149.13 and 43.36~172.68, respectively. The female had a higher NLR at age 30~49 than the male while the NLR at age 60~69 was higher in male than in female. The PLR was higher in female than in male.

conclusionThe study provides reference data on NLR and PLR from different age and sex groups in South China. NLR and PLR varied with age and sex.

Indexed as

Blood PlateletsLymphocytesNeutrophilsAdultAgedAge FactorsChinaFemaleHumansLymphocyte CountMaleMiddle AgedPlatelet CountPredictive Value of TestsReference ValuesRetrospective StudiesNeutrophil-to-lymphocyte ratioPlatelet-to-lymphocyte ratioReference range

Identifiers

PMID31132989
PMCPMC6537433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.