ArticleNeuroImage2019
TRActs constrained by UnderLying INfant anatomy (TRACULInA): An automated probabilistic tractography tool with anatomical priors for use in the newborn brain.
Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Multiscale brain development across the human lifespan.Communications biology · 2026Review
- Deep learning in fetal, infant, and toddler neuroimaging research.Developmental cognitive neuroscience · 2026Review
- Article
- White matter connections of human ventral temporal cortex are organized by cytoarchitecture, eccentricity and category-selectivity from birth.Nature human behaviour · 2025Article
- Methodological considerations on diffusion MRI tractography in infants aged 0-2 years: a scoping review.Pediatric research · 2025Article
- White matter connections of human ventral temporal cortex are organized by cytoarchitecture, eccentricity, and category-selectivity from birth.bioRxiv : the preprint server for biology · 2025Article
- Brain tissue segmentation in neurosurgery: a systematic analysis for quantitative tractography approaches.Acta neurologica Belgica · 2024Review
- Diffusion MRI with Machine Learning.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Automated three-dimensional major white matter bundle segmentation using diffusion magnetic resonance imaging.Anatomical science international · 2023Review
- Concurrent mapping of brain ontogeny and phylogeny within a common space: Standardized tractography and applications.Science advances · 2022Article
- Population-based tract-to-region connectome of the human brain and its hierarchical topology.Nature communications · 2022Article
- Quantitative mapping of the brain's structural connectivity using diffusion MRI tractography: A review.NeuroImage · 2022Review
- Review
- Using diffusion MRI data acquired with ultra-high gradient strength to improve tractography in routine-quality data.NeuroImage · 2021Article
- Article
- MRI of the Neonatal Brain: A Review of Methodological Challenges and Neuroscientific Advances.Journal of magnetic resonance imaging : JMRI · 2021Review
- Neuroimaging in infants with prenatal opioid exposure: Current evidence, recent developments and targets for future research.Journal of neuroradiology = Journal de neuroradiologie · 2021Review
- Multi-Channel 4D Parametrized Atlas of Macro- and Microstructural Neonatal Brain Development.Frontiers in neuroscience · 2021Article
- In vivo characterization of emerging white matter microstructure in the fetal brain in the third trimester.Human brain mapping · 2020Article
- Automatic, Age Consistent Reconstruction of the Corpus Callosum Guided by Coherency From In Utero Diffusion-Weighted MRI.IEEE transactions on medical imaging · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
The ongoing myelination of white-matter fiber bundles plays a significant role in brain development. However, reliable and consistent identification of these bundles from infant brain MRIs is often challenging due to inherently low diffusion anisotropy, as well as motion and other artifacts. In this paper we introduce a new tool for automated probabilistic tractography specifically designed for newborn infants. Our tool incorporates prior information about the anatomical neighborhood of white-matter pathways from a training data set. In our experiments, we evaluate this tool on data from both full-term and prematurely born infants and demonstrate that it can reconstruct known white-matter tracts in both groups robustly, even in the presence of differences between the training set and study subjects. Additionally, we evaluate it on a publicly available large data set of healthy term infants (UNC Early Brain Development Program). This paves the way for performing a host of sophisticated analyses in newborns that we have previously implemented for the adult brain, such as pointwise analysis along tracts and longitudinal analysis, in both health and disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.