Evidence map›Paper›PMID 31132067›Full record

ArticleJournal of visualized experiments : JoVE2019

Gold Nanoparticle Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection.

Sanuja Mohanaraj, Pauline Wonnenberg, Brianna Cohen, He Zhao, Matthew R Hartings, Shouzhong Zou, Douglas M Fox, Alexander G Zestos

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  7. A Straightforward Approach to Create Ag/SWCNT Composites.Materials (Basel, Switzerland) · 2021
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  9. Analytical chemistry · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sanuja MohanarajDepartment of Chemistry, American University.
Pauline WonnenbergDepartment of Chemistry, American University.
Brianna CohenDepartment of Chemistry, American University.
He ZhaoDepartment of Chemistry, American University.
Matthew R HartingsDepartment of Chemistry, American University.
Shouzhong ZouDepartment of Chemistry, American University.
Douglas M FoxDepartment of Chemistry, American University.
Alexander G ZestosDepartment of Chemistry, American University; Center for Behavioral Neuroscience, American University; zestos@american.edu.
American University · US

Funding

Multielectrode Arrays for Neurotransmitter Detection with Fast Scan Cyclic VoltammetryR41NS113702 · NINDS · MICROPROBES FOR LIFE SCIENCE, INC. · PI ZESTOS, ALEXANDROS GEORGE · 2019 to 2019
$145k
NINDS NIH HHS R41 NS113702
6 · The paper itself

Abstract

For over 30 years, carbon-fiber microelectrodes (CFMEs) have been the standard for neurotransmitter detection. Generally, carbon fibers are aspirated into glass capillaries, pulled to a fine taper, and then sealed using an epoxy to create electrode materials that are used for fast scan cyclic voltammetry testing. The use of bare CFMEs has several limitations, though. First and foremost, the carbon fiber contains mostly basal plane carbon, which has a relatively low surface area and yields lower sensitivities than other nanomaterials. Furthermore, the graphitic carbon is limited by its temporal resolution, and its relatively low conductivity. Lastly, neurochemicals and macromolecules have been known to foul at the surface of carbon electrodes where they form non-conductive polymers that block further neurotransmitter adsorption. For this study, we modify CFMEs with gold nanoparticles to enhance neurochemical testing with fast scan cyclic voltammetry. Au

Indexed as

Carbon FiberGoldMetal NanoparticlesMicroelectrodesDopamineNeurotransmitter AgentsCarbon FiberDopamineGoldNeurotransmitter Agents

Identifiers

PMID31132067
PMCPMC8266205
OpenAlexW2945342077

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.