Evidence map›Paper›PMID 31132027›Full record

ReviewCancer biology & therapy2019

Pure nongestational uterine choriocarcinoma in postmenopausal women: a case report with literature review.

Linping Wang, Yunzhe Wan, Yue Sun, Xiang Zhang, Xiaobo Cheng, Meijing Wu, Guoyan Liu

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Cancer biology & therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Linping WangDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital , Tianjin , China.
Yunzhe WanDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital , Tianjin , China.
Yue SunDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital , Tianjin , China.ORCID 0000-0002-3999-2188
Xiang ZhangDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital , Tianjin , China.
Xiaobo ChengDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital , Tianjin , China.
Meijing WuDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital , Tianjin , China.
Guoyan LiuDepartment of Gynecology and Obstetrics, Tianjin Medical University General Hospital , Tianjin , China.ORCID 0000-0001-8879-6143
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nongestational choriocarcinoma is rare, especially in postmenopausal women. It may be derived from the transformation of germ cells or dedifferentiation of other tumor tissue cells. It is usually found in the ovaries but rarely in the uterus. Pure nongestational uterine choriocarcinoma in postmenopausal women is exceptional. Thirty-four cases of choriocarcinoma have been found during the past 25 y at the Tianjin Medical University General Hospital. We retrospectively reviewed the medical records of these 34 cases and found only two cases of nongestational uterine choriocarcinoma, both of which were postmenopausal women. We also reviewed 19 other cases previously reported during the past 50 y (from 1970 to 2018) that were identified as uterine choriocarcinoma in postmenopausal women. Analysis of these combined data indicates that nongestational choriocarcinoma is a rare neoplasm in postmenopausal patients. It genetically originates entirely in the patient, and short tandem repeat (STR) analyses are usually required to differentiate gestational and nongestational choriocarcinoma. Although nongestational choriocarcinoma shows some response to chemotherapy, sensitivity is much poorer than that in gestational choriocarcinoma. The prognosis for nongestational choriocarcinoma is poor and the long-term survival rate is low.

Indexed as

PostmenopauseBiopsyChoriocarcinoma, Non-gestationalCombined Modality TherapyDisease ManagementDisease SusceptibilityFemaleHumansImmunohistochemistryMicrosatellite RepeatsMiddle AgedSymptom AssessmentUltrasonographyDNA polymorphism analysesnongestationalpostmenopausalUterine choriocarcinoma

Identifiers

PMID31132027
PMCPMC6741566
OpenAlexW2947932574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.