Evidence map›Paper›PMID 31131548›Full record

ReviewMolecular genetics & genomic medicine2019

Role of genomics literacy in reducing the burden of common genetic diseases in Africa.

Gerald Mboowa, Ivan Sserwadda

Open access · goldAbstract readReview
In one paragraph

Review in Molecular genetics & genomic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gerald MboowaDepartment of Immunology and Molecular Biology, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0001-8445-9414
Ivan SserwaddaDepartment of Immunology and Molecular Biology, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0001-7785-7297
Makerere University · UG

Funding

Phenotyping and BioarchivingU54AI110398 · NIAID · BOTSWANA BAYLOR CHILD/CLINCAL CTR/EXCELL · PI MATSHABA, MOGOMOTSI SANDY · 2014 to 2021
$8.9M
NIAID NIH HHS U54 AI110398Wellcome TrustWellcome Trust 107742/Z/15/Z
6 · The paper itself

Abstract

backgroundIn Africa, health practitioners and the current knowledge of the public on genetics and genomics is still very low and yet this has potential to reduce the burden of common genetic diseases. Many initiatives have promoted genomic research, infrastructure, and capacity building in Africa. What remains to be done is to improve genomics literacy among populations and communities while utilizing an array of strategies. Genomic literacy and awareness are key in the management of genetic diseases which includes diagnosis, prevention of complications and therapy. Africa is characterized by great cultural and language diversity thereby requiring a multidisciplinary approach to improving public and community genomics literacy and engagement. However, this is further complicated by having the fact that sub-Saharan Africa is comprised of countries with the lowest literacy rates in the world.

methodsWe applied the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to review genomic literacy in Africa using PubMed database.

resultsWe found very limited evidence of genomics literacy for genetic diseases in Africa.

conclusionWe propose a number of approaches that if adopted will significantly increase the genomic literacy and reduce the burden of genetic diseases in Africa.

Indexed as

AfricaAttitude to HealthGenetic Diseases, InbornGenomicsHealth Knowledge, Attitudes, PracticeHumansLiteracyAfricaeducationgeneticsgenomicsliteracy

Identifiers

PMID31131548
PMCPMC6625136
OpenAlexW2947239863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.