Evidence map›Paper›PMID 31131362›Full record

ArticleAnnals of gastroenterological surgery2019

Preoperative lymphocyte-to-monocyte ratio is useful for stratifying the prognosis of hepatocellular carcinoma patients with a low Cancer of the Liver Italian Program score undergoing curative resection.

Takayuki Shimizu, Mitsuru Ishizuka, Kyung Hwa Park, Takayuki Shiraki, Yuhki Sakuraoka, Shozo Mori, Yukihiro Iso, Masato Kato, Taku Aoki, Keiichi Kubota

Abstract read
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Article in Annals of gastroenterological surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takayuki ShimizuSecond Department of Surgery Dokkyo Medical University Tochigi Japan.ORCID https://orcid.org/0000-0002-2727-842X
Mitsuru IshizukaSecond Department of Surgery Dokkyo Medical University Tochigi Japan.ORCID https://orcid.org/0000-0003-3241-1480
Kyung Hwa ParkSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Takayuki ShirakiSecond Department of Surgery Dokkyo Medical University Tochigi Japan.ORCID https://orcid.org/0000-0003-2935-6708
Yuhki SakuraokaSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Shozo MoriSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Yukihiro IsoSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Masato KatoSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Taku AokiSecond Department of Surgery Dokkyo Medical University Tochigi Japan.
Keiichi KubotaSecond Department of Surgery Dokkyo Medical University Tochigi Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimAlthough the Cancer of the Liver Italian Program (CLIP) score is useful for prognostication of patients with hepatocellular carcinoma (HCC), a previous study has reported that the CLIP score was unable to stratify the postoperative outcomes of HCC patients in whom the score was low (0-1). Recent studies have reported that the preoperative lymphocyte-to-monocyte ratio (LMR) is useful for prognostication of patients with various cancer.

methodsWe reviewed 329 HCC patients with a low CLIP score (0-1) undergoing curative resection. This study had the approval of the Institutional Review Board (28068). Multivariate analyses were carried out to detect clinical factors correlating with overall survival (OS). Kaplan-Meier analysis and the log-rank test were used for comparison of OS.

resultsMultivariate analysis showed that LMR (<4.35/≥4.35) was significantly associated with OS (hazard ratio [HR], 2.022; 95% CI, 1.141-3.583;

conclusionPreoperative LMR is useful for stratifying the prognosis of HCC patients with a low CLIP score (0-1) undergoing curative resection.

Indexed as

CLIP scorecurative resectionhepatocellular carcinomalow CLIP scorelymphocyte‐to‐monocyte ratio

Identifiers

PMID31131362
PMCPMC6524078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.