Evidence map›Paper›PMID 31131342›Full record

ArticleJBMR plus2019

Effect of Direct Electrical Current on Bones Infected with

Suzannah M Schmidt-Malan, Cassandra L Brinkman, Melissa J Karau, Robert A Brown, Brian E Waletzki, Lawrence J Berglund, Audrey N Schuetz, Kerryl E Greenwood-Quaintance, Jayawant N Mandrekar, Robin Patel

Abstract read
In one paragraph

Article in JBMR plus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Suzannah M Schmidt-MalanDivision of Clinical Microbiology Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA.
Cassandra L BrinkmanDivision of Clinical Microbiology Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA.
Melissa J KarauDivision of Clinical Microbiology Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA.
Robert A BrownBiomaterials and Histomorphometry Core Laboratory Mayo Clinic Rochester MN USA.
Brian E WaletzkiBiomaterials and Histomorphometry Core Laboratory Mayo Clinic Rochester MN USA.
Lawrence J BerglundBiomechanics Research Core Laboratory Mayo Clinic Rochester MN USA.
Audrey N SchuetzDivision of Clinical Microbiology Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA.
Kerryl E Greenwood-QuaintanceDivision of Clinical Microbiology Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA.
Jayawant N MandrekarDivision of Biomedical Statistics and Informatics Department of Health Sciences Research Mayo Clinic Rochester MN USA.
Robin PatelDivision of Clinical Microbiology Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA.

Funding

The Electricidal Effect, a Novel Anti-Biofilm StrategyR01AI091594 · NIAID · MAYO CLINIC ROCHESTER · PI Haluk Beyenal, Robin Patel · 2011 to 2026
$5.5M
Molecular Detection of Biofilms on Hip and Knee ImplantsR01AR056647 · NIAMS · MAYO CLINIC ROCHESTER · PI PATEL, ROBIN · 2009 to 2020
$4.5M
Disappearance of rifampin resistance in MRSA foreign body osteomyelitisR21AI125870 · NIAID · MAYO CLINIC ROCHESTER · PI PATEL, ROBIN · 2016 to 2017
$437k
NIAID NIH HHS R01 AI091594NIAID NIH HHS R21 AI125870NIAMS NIH HHS R01 AR056647
6 · The paper itself

Abstract

We are developing electrical approaches to treat biofilm-associated orthopedic foreign-body infection. Although we have previously shown that such approaches have antibiofilm activity, the effects on bone have not been assessed. Herein, low-amperage 200 μA fixed direct current (DC) was compared with no current, in a rat femoral foreign-body infection model. In the infected group, a platinum implant seeded with

Indexed as

ANTIBIOFILM ACTIVITYBIOFILMELECTRICAL CURRENTIMPLANT INFECTION

Identifiers

PMID31131342
PMCPMC6524671

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.