Evidence map›Paper›PMID 31131288›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2019

Applications of 3D printing in small animal magnetic resonance imaging.

John C Nouls, Rohan S Virgincar, Alexander G Culbert, Nathann Morand, Dana W Bobbert, Anne D Yoder, Robert S Schopler, Mustafa R Bashir, Alexandra Badea, Ute Hochgeschwender and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

John C NoulsDuke University Medical Center, Department of Radiology, Durham, North Carolina, United States.ORCID https://orcid.org/0000-0003-2504-7625
Rohan S VirgincarDuke University, Department of Biomedical Engineering, Durham, North Carolina, United States.
Alexander G CulbertDuke University, Department of Biomedical Engineering, Durham, North Carolina, United States.
Nathann MorandEcole des Métiers, Fribourg, Switzerland.
Dana W BobbertDuke University, Office of Information Technology, Durham, North Carolina, United States.
Anne D YoderDuke University, Department of Biology, Durham, North Carolina, United States.
Robert S SchoplerDuke University, Lemur Center, Durham, North Carolina, United States.
Mustafa R BashirDuke University Medical Center, Department of Radiology, Durham, North Carolina, United States.
Alexandra BadeaDuke University Medical Center, Department of Radiology, Durham, North Carolina, United States.
Ute HochgeschwenderCentral Michigan University, College of Medicine, Mount Pleasant, Michigan, United States.
Bastiaan DriehuysDuke University Medical Center, Department of Radiology, Durham, North Carolina, United States.
Duke University · USDuke Medical Center · USOffice of the National Coordinator for Health Information Technology · US

Funding

Early Detection of Changes in Pulmonary Gas Exchange by Hyperpolarized Xe MRIR01HL105643 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2011 to 2026
$6.7M
Quantitative MR Microscopy of Phenotypic Biomarkers in Alzheimer's DiseaseK01AG041211 · NIA · DUKE UNIVERSITY · PI BADEA, ALEXANDRA · 2014 to 2018
$642k
Data commons for 'omic, microscopy and analysis core facilitiesS10OD018164 · OD · DUKE UNIVERSITY · PI WRAY, GREGORY A. · 2014 to 2014
$598k
NHLBI NIH HHS R01 HL105643NIA NIH HHS K01 AG041211NIH HHS S10 OD018164
6 · The paper itself

Abstract

Three-dimensional (3D) printing has significantly impacted the quality, efficiency, and reproducibility of preclinical magnetic resonance imaging. It has vastly expanded the ability to produce MR-compatible parts that readily permit customization of animal handling, achieve consistent positioning of anatomy and RF coils promptly, and accelerate throughput. It permits the rapid and cost-effective creation of parts customized to a specific imaging study, animal species, animal weight, or even one unique animal, not routinely used in preclinical research. We illustrate the power of this technology by describing five preclinical studies and specific solutions enabled by different 3D printing processes and materials. We describe fixtures, assemblies, and devices that were created to ensure the safety of anesthetized lemurs during an MR examination of their brain or to facilitate localized, contrast-enhanced measurements of white blood cell concentration in a mouse model of pancreatitis. We illustrate expansive use of 3D printing to build a customized birdcage coil and components of a ventilator to enable imaging of pulmonary gas exchange in rats using hyperpolarized

Indexed as

3D printingadditive manufacturinganimalmagnetic resonance imagingpreclinical

Identifiers

PMID31131288
PMCPMC6519666
OpenAlexW2945402187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.