Evidence map›Paper›PMID 31131263›Full record

ArticleFrontiers in cellular and infection microbiology2019

TLR4 Participates in the Inflammatory Response Induced by the AAF/II Fimbriae From Enteroaggregative

Alejandra Alvestegui, Mauricio Olivares-Morales, Ernesto Muñoz, Rachel Smith, James P Nataro, Fernando Ruiz-Perez, Mauricio J Farfan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. MucoidFrontiers in medicine · 2022
    Article
  5. Virulence Factors of Enteric PathogenicInternational journal of molecular sciences · 2021
    Review
  6. Review
  7. Gut Microbiota-Metabolome Changes in Children With Diarrhea by DiarrheagenicFrontiers in cellular and infection microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Alejandra AlvesteguiDepartamento de Pediatría, Facultad de Medicina, Centro de Estudios Moleculares, Hospital Dr. Luis Calvo Mackenna, Universidad de Chile, Santiago, Chile.
Mauricio Olivares-MoralesDepartamento de Pediatría, Facultad de Medicina, Centro de Estudios Moleculares, Hospital Dr. Luis Calvo Mackenna, Universidad de Chile, Santiago, Chile.
Ernesto MuñozDepartamento de Pediatría, Facultad de Medicina, Centro de Estudios Moleculares, Hospital Dr. Luis Calvo Mackenna, Universidad de Chile, Santiago, Chile.
Rachel SmithDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, United States.
James P NataroDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, United States.
Fernando Ruiz-PerezDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA, United States.
Mauricio J FarfanDepartamento de Pediatría, Facultad de Medicina, Centro de Estudios Moleculares, Hospital Dr. Luis Calvo Mackenna, Universidad de Chile, Santiago, Chile.
Hospital Luis Calvo Mackenna · CLUniversity of Virginia · USUniversity of Chile · CL

Funding

Virulence in Enteroaggregative Escherichia coliR01AI033096 · NIAID · UNIVERSITY OF VIRGINIA · PI NATARO, JAMES P. · 1996 to 2014
$6.6M
NIAID NIH HHS R01 AI033096
6 · The paper itself

Abstract

Enteroaggregative

Indexed as

CytokinesEpithelial CellsEscherichia coliEscherichia coli InfectionsFimbriae, BacterialHT29 CellsHumansInflammationInterleukin-4Interleukin-8IntestinesToll-Like Receptor 2Toll-Like Receptor 4CytokinesIL4 protein, humanInterleukin-4Interleukin-8TLR2 protein, humanTLR4 protein, humanToll-Like Receptor 2Toll-Like Receptor 4Aggregative adherence fimbriaeenteroaggregative E. coliinflammationinterleukin-8toll-like receptors

Identifiers

PMID31131263
PMCPMC6509964
OpenAlexW2941162958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.