Evidence map›Paper›PMID 31131158›Full record

ArticleInternational journal of medical physics, clinical engineering and radiation oncology2018

Technical Note: Identification of CT Texture Features Robust to Tumor Size Variations for Normal Lung Texture Analysis.

Wookjin Choi, Sadegh Riyahi, Seth J Kligerman, Chia-Ju Liu, James G Mechalakos, Wei Lu

Open access · diamondAbstract read
In one paragraph

Article in International journal of medical physics, clinical engineering and radiation oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wookjin ChoiDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Sadegh RiyahiDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Seth J KligermanDepartment of Radiology, University of California at San Diego, San Diego, CA 92103.
Chia-Ju LiuDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
James G MechalakosDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Wei LuDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Memorial Sloan Kettering Cancer Center · USUniversity of California, San Diego · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Quantitative PET/CT Analysis to Improve Evaluation of Tumor ResponseR01CA172638 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI LU, WEI · 2013 to 2016
$1.3M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA172638
6 · The paper itself

Abstract

Normal lung CT texture features have been used for the prediction of radiation-induced lung disease (RILD). For these features to be clinically useful, they should be robust to tumor size variations and not correlated with the normal lung volume of interest, i.e., the volume of the peri-tumoral region (PTR). CT images of 14 lung cancer patients were studied. Different sizes of gross tumor volumes (GTVs) were simulated and placed in the lung contralateral to the tumor. 27 texture features [nine from intensity histogram, eight from the gray-level co-occurrence matrix (GLCM) and ten from the gray-level run-length matrix (GLRM)] were extracted from the PTR. The Bland-Altman analysis was applied to measure the normalized range of agreement (nRoA) for each feature when GTV size varied. A feature was considered as robust when its nRoA was less than the threshold (100%). Sixteen texture features were identified as robust. None of the robust features was correlated with the volume of the PTR. No feature showed statistically significant differences (P<0.05) on GTV locations. We identified 16 robust normal lung CT texture features that can be further examined for the prediction of RILD.

Indexed as

CTNormal lung textureRadiation-induced lung diseaseRadiomicsStereotactic body radiotherapy

Identifiers

PMID31131158
PMCPMC6530926
OpenAlexW2887831780

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.