ArticleJournal of global health2019
Epidemiology of viral acute lower respiratory infections in a community-based cohort of rural north Indian children.
Article in Journal of global health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Disease burden due to respiratory syncytial virus infection among under-5 children of India for 2020: a multiplicative model using meta-estimates.BMJ global health · 2025Pooled it
- Oral Selenium as an Adjunct in the Treatment of Acute Lower Respiratory Tract Infections in Children: A Double-Blind Randomized Controlled Trial.Indian pediatrics · 2025Trial
- Efficacy of live attenuated and inactivated influenza vaccines among children in rural India: A 2-year, randomized, triple-blind, placebo-controlled trial.PLoS medicine · 2021Trial
- Trends of severe human metapneumovirus infections in India.BMC infectious diseases · 2026Article
- Acute Respiratory Tract Infections and Severe Disease Among Hospitalized Children.JAMA network open · 2026Article
- Predicting societal risk factors for respiratory co-infections: a cross-sectional study based on multi-source fever clinic data.BMC infectious diseases · 2026Article
- Epidemiological analysis of six common respiratory pathogen infections in children in Chengdu from 2022 to 2024.Frontiers in pediatrics · 2026Article
- Efficacy of prophylactic intermittent zinc supplementation for reducing acute respiratory infections and diarrhoea in infants: A randomized controlled trial.World journal of clinical pediatrics · 2025Article
- Development and clinical application of a rapid qPCR instrument featuring three independent temperature modules and a time-based algorithm for respiratory pathogen diagnosis.Virology journal · 2025Article
- Epidemiology and surveillance of influenza, RSV and SARS-CoV-2 in children admitted with severe acute respiratory infection in West bengal, India from 2022 to 2023.BMC infectious diseases · 2025Article
- Respiratory syncytial virus hospitalization costs, rates, and seasonality in Asia: a systematic review and meta-analysis.EClinicalMedicine · 2025Review
- Respiratory viruses associated with severe acute respiratory infection in children aged <5 years at a tertiary care hospital in Delhi, India during 2013-15.Journal of global health · 2024Article
- Pan-India influenza-like illness (ILI) and Severe acute respiratory infection (SARI) surveillance: epidemiological, clinical and genomic analysis.Frontiers in public health · 2023Article
- Respiratory Syncytial Virus Incidence and Severity in a Community-Based Prospective Cohort of Children Aged 0-14 Years.Open forum infectious diseases · 2022Article
- Incidence of lower respiratory tract infection and associated viruses in a birth cohort in the Philippines.BMC infectious diseases · 2022Article
- Incidence, risk factors, and viral etiology of community-acquired acute lower respiratory tract infection among older adults in rural north India.Journal of global health · 2021Article
- Epidemiological characteristics of four common respiratory viral infections in children.Virology journal · 2021Article
- The Burden of Respiratory Viruses and Their Prevalence in Different Geographical Regions of India: 1970-2020.Frontiers in microbiology · 2021Review
- Disease Burden Due to Respiratory Syncytial Virus in Indian Pediatric Population: A Literature Review.Clinical medicine insights. Pediatrics · 2021Review
- Considering Interim Interventions to Control COVID-19 Associated Morbidity and Mortality-Perspectives.Frontiers in public health · 2020Article
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Authors and funding
17 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundIn India, community-based acute lower respiratory infections (ALRI) burden studies are limited, hampering development of prevention and control strategies.
methodsWe surveyed children <10 years old at home weekly from August 2012-August 2014, for cough, sore throat, rhinorrhoea, ear discharge, and shortness of breath. Symptomatic children were assessed for ALRI using World Health Organization definitions. Nasal and throat swabs were obtained from all ALRI cases and asymptomatic controls and tested using polymerase chain reaction for respiratory syncytial virus (RSV), human metapneumovirus (hMPV), parainfluenza viruses (PIV), and influenza viruses (IV). We estimated adjusted odds ratios (aOR) using logistic regression to calculate etiologic fractions (EF). We multiplied agent-specific ALRI incidence rates by EF to calculate the adjusted incidence as episodes per child-year.
resultsALRI incidence was 0.19 (95% confidence interval (CI) = 0.18-0.20) episode per child-year. Association between virus and ALRI was strongest for RSV (aOR = 15.9; 95% CI = 7.3-34.7; EF = 94%) and least for IV (aOR = 4.6; 95% CI = 2.0-10.6; EF = 78%). Adjusted agent-specific ALRI incidences were RSV (0.03, 95% CI = 0.02-0.03), hMPV (0.02, 95% CI = 0.01-0.02), PIV (0.02, 95% CI = 0.01-0.02), and IV (0.01, 95% CI = 0.01-0.01) episode per child-year.
conclusionsALRI among children in rural India was high; RSV was a significant contributor.
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