Evidence map›Paper›PMID 31131059›Full record

ArticleTheranostics2019

Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events

Ryo Nishihara, Ramasamy Paulmurugan, Takahiro Nakajima, Eiji Yamamoto, Arutselvan Natarajan, Rayhaneh Afjei, Yuki Hiruta, Naoko Iwasawa, Shigeru Nishiyama, Daniel Citterio and 3 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Optical and Photoacoustic Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  4. Article
  5. The latest developments of near-infrared fluorescent probes from NIR-I to NIR-II for bioimaging.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Bioluminescent imaging systems boosting near-infrared signals in mammalian cells.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. C-Series Coelenterazine-Driven Bioluminescence Signature Imaging.International journal of molecular sciences · 2022
    Article
  16. Article
  17. Article
  18. How to Select Firefly Luciferin Analogues for In Vivo Imaging.International journal of molecular sciences · 2021
    Review
  19. Bioluminescent Imaging Systems for Assay Developments.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Ryo NishiharaDepartment of Applied Chemistry, Faculty of Science and Technology, Graduate School of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
Ramasamy PaulmuruganMolecular Imaging Program at Stanford, Bio-X Program, Stanford University School of Medicine, Palo Alto, California 94304, United States.
Takahiro NakajimaGraduate School of Arts and Sciences, The University of Tokyo, 3-8-1, Komaba Meguro-ku, Tokyo 153-8902, Japan.
Eiji YamamotoGraduate School of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
Arutselvan NatarajanMolecular Imaging Program at Stanford, Bio-X Program, Stanford University School of Medicine, Palo Alto, California 94304, United States.
Rayhaneh AfjeiMolecular Imaging Program at Stanford, Bio-X Program, Stanford University School of Medicine, Palo Alto, California 94304, United States.
Yuki HirutaDepartment of Applied Chemistry, Faculty of Science and Technology, Graduate School of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
Naoko IwasawaDepartment of Applied Chemistry, Faculty of Science and Technology, Graduate School of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
Shigeru NishiyamaDepartment of Applied Chemistry, Faculty of Science and Technology, Graduate School of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
Daniel CitterioDepartment of Applied Chemistry, Faculty of Science and Technology, Graduate School of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
Moritoshi SatoGraduate School of Arts and Sciences, The University of Tokyo, 3-8-1, Komaba Meguro-ku, Tokyo 153-8902, Japan.
Sung Bae KimMolecular Imaging Program at Stanford, Bio-X Program, Stanford University School of Medicine, Palo Alto, California 94304, United States.
Koji SuzukiDepartment of Applied Chemistry, Faculty of Science and Technology, Graduate School of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.
Keio University · JPStanford University · USThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amino Acid SequenceAnimalsBinding SitesBreast NeoplasmsChlorocebus aethiopsCOS CellsFemaleFluorescence Resonance Energy TransferHeLa CellsHeterograftsHumansImidazolesLiver NeoplasmsLuciferasesLuminescent AgentsLuminescent MeasurementscoelenterazineImidazolesLuciferasesLuminescent AgentsLuminescent ProteinsPyrazinesReceptors, EstrogenRecombinant Fusion ProteinsRed Fluorescent ProteinBioluminescence Imagingbioluminescence resonance energy transfer (BRET)blue-to-near infrared shiftcoelenterazine derivativesmetastasis

Identifiers

PMID31131059
PMCPMC6525985
OpenAlexW2937786562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.