ReviewFrontiers in genetics2019
Sex Difference of Radiation Response in Occupational and Accidental Exposure.
Review in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The risk of thyroid cancer in relation to residential proximity to nuclear power plants: a systematic review and meta-analysis.Environmental health : a global access science source · 2024Pooled it
- Ionizing radiation exposure during adulthood and risk of developing central nervous system tumors: systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Local treatment options for young women with ductal carcinoma in situ: A systematic review and meta-analysis comparing breast conserving surgery with or without adjuvant radiotherapy, and mastectomy.Breast (Edinburgh, Scotland) · 2022Pooled it
- Sex differences in a mouse model of radiation-induced cardiomyopathy.Biology of sex differences · 2026Article
- Women in space: A review of known physiological adaptations and health perspectives.Experimental physiology · 2026Review
- Effective Dose Evaluation of Cerebral Angiography Using Kerma Area Product and Development of Effective Dose Conversion Factors.Diagnostics (Basel, Switzerland) · 2026Article
- Subsequent Neoplasm Risk After Modern Mediastinal Radiation Therapy for Pediatric Hodgkin Lymphoma: Insights From a Multi-Institutional Children's Oncology Group Trial.International journal of radiation oncology, biology, physics · 2026Article
- LA-GM-CSF, a Long-Acting Cytokine Mitigates and Prevents H-ARS Mediated Lethality in Mice Exposed to Total Body Gamma Radiation.International journal of molecular sciences · 2026Article
- Clinical Feasibility of Robotic-Assisted Endovascular Visceral Interventions.Cardiovascular and interventional radiology · 2026Article
- Quantitative Assessment of the Effects of Scatter Radiation on Image Quality During Extremity Radiography at a Leading Tertiary Hospital in Ghana: An Experimental Pilot Study.Health science reports · 2026Article
- Sex-dependent PRRT toxicity in patients with metastatic somatostatin receptor-avid neuroendocrine tumors treated withHormones (Athens, Greece) · 2026Article
- Sex-dependent PRRT toxicity in patients with metastatic somatostatin receptor-avid neuroendocrine tumors treated withHormones (Athens, Greece) · 2026Article
- Detection of germline variants in human population chronically exposed to high level natural background radiation in Kerala coast.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2026Article
- Low-dose X-Ray induced genetic damage in human peripheral blood lymphocytes.Frontiers in genetics · 2026Article
- Review
- Sexual dimorphism inScientific reports · 2025Article
- Exposure to protracted low-dose ionizing radiation and incident dementia in a cohort of Ontario nuclear power plant workers.Scandinavian journal of work, environment & health · 2025Article
- Dose Reduction by Field of View Optimisation in Cone-Beam Computed Tomography of Unilateral Alveolar Clefts.Orthodontics & craniofacial research · 2025Article
- Age-Stratified Spatial Radiological Risk Assessment ofJournal of xenobiotics · 2025Article
- Radiation protection: safety measures and knowledge among interventional radiologists- a UK-based analysis of current practices and recommendations for improvement.CVIR endovascular · 2025Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ionizing radiation is a well-established cause of deleterious effects on human health. Understanding the risks of radiation exposure is important for the development of protective measures and guidelines. Demographic factors such as age, sex, genetic susceptibility, comorbidities, and various other lifestyle factors influence the radiosensitivity of different subpopulations. Amongst these factors, the influence of sex differences on radiation sensitivity has been given very less attention. In fact, the International Commission on Radiological Protection (ICRP) has based its recommendations on a population average, rather than the data on the radiosensitivity of distinct subpopulations. In this study, we reviewed major human studies on the health risks of radiation exposure and showed that sex-related factors may potentially influence the long-term response to radiation exposure. Available data suggest that long-term radiosensitivity in women is higher than that in men who receive a comparable dose of radiation. The report on the biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences, United States emphasized that women may be at significantly greater risk of suffering and dying from radiation-induced cancer than men exposed to the same dose of radiation. We show that radiation effects are sex-specific, and long-term radiosensitivity in females is higher than that in males. We also discuss the radiation effects as a function of age. In the future, more systematic studies are needed to elucidate the sex differences in radiation responses across the life continuum - from preconception through childhood, adulthood, and old age - to ensure that boys and girls and men and women are equally protected across ages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.