Evidence map›Paper›PMID 31130968›Full record

ArticleFrontiers in immunology2019

Effects of Sweet Cherry Polyphenols on Enhanced Osteoclastogenesis Associated With Childhood Obesity.

Filomena Corbo, Giacomina Brunetti, Pasquale Crupi, Sara Bortolotti, Giuseppina Storlino, Laura Piacente, Alessia Carocci, Alessia Catalano, Gualtiero Milani, Graziana Colaianni and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

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  10. Phytochemical Characterization of a Tree Tomato (Plants (Basel, Switzerland) · 2022
    Article
  11. Article
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  13. Review
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  15. Ethanol Extract ofMolecules (Basel, Switzerland) · 2021
    Article
  16. Nutrients · 2020
    Review
  17. Article
  18. International journal of molecular sciences · 2020
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Filomena CorboDepartment of Pharmacy-Drug science, University of Bari Aldo Moro, Bari, Italy.
Giacomina BrunettiSection of Human Anatomy and Histology, Department of Basic and Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
Pasquale CrupiCREA-VE, Council for Agricultural Research and Economics-Research Centre for Viticulture and Enology, Turi, Italy.
Sara BortolottiSection of Human Anatomy and Histology, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Giuseppina StorlinoSection of Human Anatomy and Histology, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Laura PiacentePaediatric Unit, Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, Bari, Italy.
Alessia CarocciDepartment of Pharmacy-Drug science, University of Bari Aldo Moro, Bari, Italy.
Alessia CatalanoDepartment of Pharmacy-Drug science, University of Bari Aldo Moro, Bari, Italy.
Gualtiero MilaniDepartment of Pharmacy-Drug science, University of Bari Aldo Moro, Bari, Italy.
Graziana ColaianniSection of Human Anatomy and Histology, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Silvia ColucciSection of Human Anatomy and Histology, Department of Basic and Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
Maria GranoSection of Human Anatomy and Histology, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Carlo FranchiniDepartment of Pharmacy-Drug science, University of Bari Aldo Moro, Bari, Italy.
Maria Lisa ClodoveoInterdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy.
Gabriele D'AmatoNeonatal Intensive Care Unit, Di Venere Hospital, Bari, Italy.
Maria Felicia FaienzaPaediatric Unit, Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, Bari, Italy.
University of Bari Aldo Moro · ITCereal Research Centre · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood obesity is associated with the development of severe comorbidities, such as diabetes, cardiovascular diseases, and increased risk of osteopenia/osteoporosis and fractures. The status of low-grade inflammation associated to obesity can be reversed through an enhanced physical activity and by consumption of food enrich of anti-inflammatory compounds, such as omega-3 fatty acids and polyphenols. The aim of this study was to deepen the mechanisms of bone impairment in obese children and adolescents through the evaluation of the osteoclastogenic potential of peripheral blood mononuclear cells (PBMCs), and the assessment of the serum levels of RANKL and osteoprotegerin (OPG). Furthermore, we aimed to evaluate the

Indexed as

Pediatric ObesityPrunus aviumAdolescentCells, CulturedChildDietary SupplementsFemaleHumansLeukocytes, MononuclearMaleOsteoclastsOsteogenesisOsteoprotegerinPolyphenolsRANK LigandTumor Necrosis Factor-alphaOsteoprotegerinPolyphenolsRANK LigandTNF protein, humanTNFSF11 protein, humanTumor Necrosis Factor-alphaCD14+/CD16+ monocytesinflammationobesityosteoclastogenesisosteopeniaosteoporosispolyphenolssweet cherry

Identifiers

PMID31130968
PMCPMC6509551
OpenAlexW2941109253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.