Evidence map›Paper›PMID 31130911›Full record

ArticleFrontiers in neurology2019

Thalamic Atrophy Without Whole Brain Atrophy Is Associated With Absence of 2-Year NEDA in Multiple Sclerosis.

Katariina Hänninen, Matias Viitala, Teemu Paavilainen, Jari O Karhu, Juha Rinne, Juha Koikkalainen, Jyrki Lötjönen, Merja Soilu-Hänninen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Neurodegeneration in multiple sclerosis.WIREs mechanisms of disease · 2023
    Review
  10. Review
  11. Article
  12. Predictive MRI Biomarkers in MS-A Critical Review.Medicina (Kaunas, Lithuania) · 2022
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Aggressive multiple sclerosis (1): Towards a definition of the phenotype.Multiple sclerosis (Houndmills, Basingstoke, England) · 2020
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Katariina HänninenDivision of Clinical Neurosciences, Turku University Hospital, University of Turku, Turku, Finland.
Matias ViitalaDepartment of Mathematics and Statistics, University of Turku, Turku, Finland.
Teemu PaavilainenMedical Imaging Centre of Southwest Finland, Turku, Finland.
Jari O KarhuMedical Imaging Centre of Southwest Finland, Turku, Finland.
Juha RinneDivision of Clinical Neurosciences, Turku University Hospital, University of Turku, Turku, Finland.
Juha KoikkalainenCombinostics Ltd., Tampere, Finland.
Jyrki LötjönenTurku PET Centre, University of Turku, Turku, Finland.
Merja Soilu-HänninenDivision of Clinical Neurosciences, Turku University Hospital, University of Turku, Turku, Finland.
Turku University Hospital · FIUniversity of Turku · FIVarsinais-Suomen Sairaanhoitopiiri · FITurku PET Centre · FI

Funding

Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain atrophycognitiondisabilitymagnetic resonance imagingmultiple sclerosisNEDAthalamus

Identifiers

PMID31130911
PMCPMC6509198
OpenAlexW2942786854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.