Evidence map›Paper›PMID 31130747›Full record

ReviewReumatologia2019

Determination of antibodies in everyday rheumatological practice.

Katarzyna Napiórkowska-Baran, Joanna Zalewska, Sławomir Jeka, Iwona Dankiewicz-Fares, Marcin Ziętkiewicz, Ewa Szynkiewicz, Sylwia Kołtan, Adam Wawrzeńczyk, Ewa Więsik-Szewczyk, Zbigniew Bartuzi

Abstract readReview
In one paragraph

Review in Reumatologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katarzyna Napiórkowska-BaranDepartment of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Joanna ZalewskaClinic of Rheumatology and Connective Tissue Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Sławomir JekaClinic of Rheumatology and Connective Tissue Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Iwona Dankiewicz-FaresClinic of Rheumatology and Connective Tissue Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Marcin ZiętkiewiczDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdansk, Poland.
Ewa SzynkiewiczDepartment of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Sylwia KołtanDepartment of Paediatrics, Haematology and Oncology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Adam WawrzeńczykDepartment of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Ewa Więsik-SzewczykDepartment of Internal Medicine, Pneumonology, Allergology, and Clinical Immunology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine, Warsaw, Poland.
Zbigniew BartuziDepartment of Allergology, Clinical Immunology and Internal Diseases, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody determination is routinely used in everyday rheumatological practice. Its result repeatedly determines the diagnosis or exclusion of a particular disease. Antibodies are immunoglobulins, i.e. some of the most important proteins in the immune system, and have specific properties that we should know. In addition, there are a number of factors that can affect their concentration, including drugs commonly used in the treatment of rheumatic diseases. There are definite indications, when the total concentrations of individual classes of immunoglobulins should be initially determined and it should be evaluated whether the patient produces them at all or their production is impaired. In some cases, we should evaluate the levels of specific antibodies along with the total protein concentration and the γ-globulin fraction, in which the antibodies are contained. The article presents information on the most common mistakes made when performing these tests.

Indexed as

antibodiesimmunoglobulinsrheumatic diseases

Identifiers

PMID31130747
PMCPMC6532108

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.