Evidence map›Paper›PMID 31130716›Full record

ArticleCancers2019

Living Donor Liver Re-Transplantation for Recurrent Hepatoblastoma in the Liver Graft following Complete Eradication of Peritoneal Metastases under Indocyanine Green Fluorescence Imaging.

Nobuhiro Takahashi, Yohei Yamada, Ken Hoshino, Miho Kawaida, Teizaburo Mori, Kiyotomo Abe, Takumi Fujimura, Kentaro Matsubara, Taizo Hibi, Masahiro Shinoda and 8 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Nobuhiro TakahashiDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. tkhsnbhr430@gmail.com.ORCID 0000-0003-2508-8419
Yohei YamadaDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. yohei@z7.keio.jp.
Ken HoshinoDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. hoshino@z7.keio.jp.ORCID 0000-0002-3021-3029
Miho KawaidaDepartment of Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan. m.kawaida@a2.keio.jp.
Teizaburo MoriDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. 0105mori@keio.jp.
Kiyotomo AbeDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. matuzono300@yahoo.co.jp.
Takumi FujimuraDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. fujitaku3@gmail.com.
Kentaro MatsubaraDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. kmatsubaravs@gmail.com.
Taizo HibiDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. taizohibi@gmail.com.ORCID 0000-0002-6867-228X
Masahiro ShinodaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. masa02114@yahoo.co.jp.
Hideaki ObaraDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. obara@z3.keio.jp.
Kyohei IsshikiDepartment of Pediatrics, Keio University School of Medicine, Tokyo 160-8582, Japan. scratchbeetle@hotmail.com.
Haruko ShimaDepartment of Pediatrics, Keio University School of Medicine, Tokyo 160-8582, Japan. sharuko@keio.jp.
Hiroyuki ShimadaDepartment of Pediatrics, Keio University School of Medicine, Tokyo 160-8582, Japan. hshimada@a5.keio.jp.
Kaori KameyamaDepartment of Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan. kameyama@a5.keio.jp.
Yasushi FuchimotoDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. yfuchimoto@keio.jp.
Yuko KitagawaDepartment of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. kitagawa@a3.keio.jp.
Tatsuo KurodaDepartment of Pediatric Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan. kuroda-t@z8.keio.jp.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The curability of chemotherapy-resistant hepatoblastoma (HB) largely depends on the achievement of radical surgical resection. Navigation techniques utilizing indocyanine green (ICG) are a powerful tool for detecting small metastatic lesions. We herein report a patient who underwent a second living donor liver transplantation (LDLTx) for multiple recurrent HBs in the liver graft following metastasectomy for peritoneal dissemination with ICG navigation. The patient initially presented with ruptured HB at 6 years of age and underwent 3 liver resections followed by the first LDLTx with multiple sessions of chemotherapy at 11 years of age. His alpha-fetoprotein (AFP) level increased above the normal limit, and metastases were noted in the transplanted liver and peritoneum four years after the first LDLTx. The patient underwent metastasectomy of the peritoneally disseminated HBs with ICG navigation followed by the second LDLTx for multiple metastases in the transplanted liver. The patient has been recurrence-free with a normal AFP for 30 months since the second LDLTx. To our knowledge, this report is the first successful case of re-LDLTx for recurrent HBs. Re-LDLTx for recurrent HB can be performed in highly select patients, and ICG navigation is a powerful surgical tool for achieving tumor clearance.

Indexed as

hepatoblastomaindocyanine greenliving donor liver transplantationtransplant oncology

Identifiers

PMID31130716
PMCPMC6562613
OpenAlexW2945757849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.