Evidence map›Paper›PMID 31130610›Full record

ArticleDiseases (Basel, Switzerland)2019

Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis.

Lourdes Roman-Malo, Beatriz Bullon, Manuel de Miguel, Pedro Bullon

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diseases (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. Review
  5. A novel geneeLife · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lourdes Roman-MaloDepartment of Periodontology, Facultad de Odontologia Universidad de Sevilla, c/Avicena s/n, 41009 Sevilla, Spain. lvrmalo@gmail.com.
Beatriz BullonDepartment of Periodontology, Facultad de Odontologia Universidad de Sevilla, c/Avicena s/n, 41009 Sevilla, Spain. beatrizbullon@hotmail.com.
Manuel de MiguelDepartment of Cytology and Normal Histology and Pathologogy, Facultad de Medicina, Universidad de Sevilla, Avda. Sánchez Pizjuán s/n, 41009 Sevilla, Spain. mmiguel@us.es.ORCID 0000-0002-6751-1695
Pedro BullonDepartment of Periodontology, Facultad de Odontologia Universidad de Sevilla, c/Avicena s/n, 41009 Sevilla, Spain. pbullon@us.es.ORCID 0000-0003-4873-4196
Universidad de Sevilla · ES

Funding

Grupo de Investigacion Junta de Andalucia, Consejería de Salud of the Junta de Andalucia CTS113
6 · The paper itself

Abstract

Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts and histological alterations to give new clues. A father and a daughter of a family showing gingival hereditary fibromatosis were treated, and gingival biopsies were obtained. A histological study revealed dense fibrous tissue, basal lamina disruption, and epithelial cell migration into the connective tissue. Fibroblasts were cultured from the father and daughter and compared with those from a healthy control patient. The results of the biochemical analysis showed increased collagen synthesis, reduced antioxidant CoQ

Indexed as

antioxidantscollagenfibroblastsgingival fibromatosisgingival overgrowthoxidative stress

Identifiers

PMID31130610
PMCPMC6631910
OpenAlexW2945407052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.