Evidence map›Paper›PMID 31129986›Full record

ReviewAngiology2020

Premature Myocardial Infarction in the Middle East and North Africa: Rationale for the Gulf PREVENT Study.

Sagar B Dugani, Waheed Murad, Karisamae Damilig, Jean Atos, Eshraga Mohamed, Edward Callachan, Zareen Farukhi, Arshia Shaikh, Abubaker Elfatih, Salwa Yusef and 9 more

Abstract readReview
In one paragraph

Review in Angiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  4. Article
  5. Review
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  8. Review
  9. Article
  10. Article
  11. Premature Myocardial Infarction: A Community Study.Mayo Clinic proceedings. Innovations, quality & outcomes · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sagar B DuganiDivision of Hospital Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0001-7858-1317
Waheed MuradInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Karisamae DamiligInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Jean AtosInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Eshraga MohamedInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Edward CallachanDivision of Emergency Medicine, University of Cape Town, Cape Town, South Africa.
Zareen FarukhiCenter for Lipid Metabolomics, Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Arshia ShaikhInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Abubaker ElfatihDepartment of Pathology and Laboratory Medicine, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Salwa YusefDepartment of Pathology and Laboratory Medicine, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Yousif M HydoubDepartment of Medicine, Al-Mafraq Hospital, Abu Dhabi, UAE.ORCID https://orcid.org/0000-0001-6034-8920
M Vinayaga MoorthyCenter for Lipid Metabolomics, Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Bassem MoraInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Ahlam AlawadhiInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Robin IssacInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Abdulkarim SalehDepartment of Medicine, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Arif Al-MullaInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.
Samia MoraCenter for Lipid Metabolomics, Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Alawi A Alsheikh-AliInstitute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.

Funding

Training Program in the Epidemiology of CVDT32HL007575 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI BURING, JULIE E., RIDKER, PAUL M. · 1985 to 2019
$5.0M
Reducing Inflammation for the Prevention of CVD: A Focus on Eicosanoid PathwaysR01HL134811 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MORA, SAMIA · 2017 to 2020
$3.0M
Circulating plasma metabolites, diet, and risk of type 2 diabetesR01DK112940 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, FRANK B, MORA, SAMIA · 2018 to 2021
$2.9M
Patient Centered Approaches to Preventing ASCVD EventsK24HL136852 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SAMIA MORA · 2018 to 2026
$1.1M
NHLBI NIH HHS K24 HL136852NHLBI NIH HHS R01 HL134811NHLBI NIH HHS T32 HL007575NIDDK NIH HHS R01 DK112940
6 · The paper itself

Abstract

The Middle East and North Africa (MENA) region has a high burden of morbidity and mortality due to premature (≤55 years in men; ≤65 years in women) myocardial infarction (MI) and acute coronary syndrome (ACS). Despite this, the prevalence of risk factors in patients presenting with premature MI or ACS is incompletely described. We compared lifestyle, clinical risk factors, and biomarkers associated with premature MI/ACS in the MENA region with selected non-MENA high-income countries. We identified English-language, peer-reviewed publications through PubMed (up to March 2018). We used the World Bank classification system to categorize countries. Patients with premature MI/ACS in the MENA region had a higher prevalence of smoking than older patients with MI/ACS but a lower prevalence of diabetes, hypertension, and dyslipidemia. Men with premature MI/ACS had a higher prevalence of smoking than women but a lower prevalence of diabetes and hypertension. The MENA region had sparse data on lifestyle, diet, psychological stress, and physical activity. To address these knowledge gaps, we initiated the ongoing Gulf Population Risks and Epidemiology of Vascular Events and Treatment (Gulf PREVENT) case-control study to improve primary and secondary prevention of premature MI in the United Arab Emirates, a high-income country in the MENA region.

Indexed as

Acute Coronary SyndromeAfrica, NorthernAgedAge of OnsetCase-Control StudiesComorbidityDiabetes MellitusDyslipidemiasFemaleHumansHypertensionMaleMiddle AgedMiddle EastMortality, PrematureMyocardial Infarctionbiomarkerscardiovascular diseaseischemic heart diseaseMENApremature myocardial infarctionrisk factorsUnited Arab Emirates

Identifiers

PMID31129986
PMCPMC6878147

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.