Evidence map›Paper›PMID 31129983›Full record

Trial reportCanadian journal of psychiatry. Revue canadienne de psychiatrie2019

Cognitive Behavioural Therapy for Nightmares for Patients with Persecutory Delusions (Nites): An Assessor-Blind, Pilot Randomized Controlled Trial.

Bryony Sheaves, Emily A Holmes, Stephanie Rek, Kathryn M Taylor, Alecia Nickless, Felicity Waite, Anne Germain, Colin A Espie, Paul J Harrison, Russell Foster and 1 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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  12. Nightmare frequency and nightmare distress in psychiatric inpatients.European archives of psychiatry and clinical neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Bryony SheavesDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.ORCID 0000-0002-2995-193X
Emily A HolmesDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Stephanie RekDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Kathryn M TaylorNuffield Department of Primary Care Health Sciences, Primary Care Clinical Trials Unit, University of Oxford, Radcliffe Observatory Quarter, Oxford, UK.
Alecia NicklessNuffield Department of Primary Care Health Sciences, Primary Care Clinical Trials Unit, University of Oxford, Radcliffe Observatory Quarter, Oxford, UK.
Felicity WaiteDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Anne GermainDepartment of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Colin A EspieNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Paul J HarrisonDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Russell FosterNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Daniel FreemanOxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Oxford Health NHS Foundation Trust · GBUniversity of Oxford · GBUniversity of Pittsburgh · USUppsala University · SEWarneford Hospital · GB

Funding

Department of HealthWellcome Trust
6 · The paper itself

Abstract

objectiveNightmares are relatively common in patients experiencing psychosis but rarely assessed or treated. Nightmares may maintain persecutory delusions by portraying fears in sensory-rich detail. We tested the potential benefits of imagery-focused cognitive behavioural therapy (CBT) for nightmares on nightmare severity and persecutory delusions.

methodThis assessor-blind parallel-group pilot trial randomized 24 participants with nightmares and persecutory delusions to receive CBT for nightmares delivered over 4 weeks in addition to treatment as usual (TAU) or TAU alone. Assessments were at 0, 4 (end of treatment), and 8 weeks (follow-up). Feasibility outcomes assessed therapy uptake, techniques used, satisfaction, and attrition. The primary efficacy outcome assessed nightmare severity at week 4. Analyses were intention to treat, estimating treatment effect with 95% confidence intervals (CIs).

resultsAll participants offered CBT completed therapy (mean [SD], 4.8 [0.6] sessions) with high satisfaction, and 20 (83%) participants completed all assessments. Compared with TAU, CBT led to large improvements in nightmares (adjusted mean difference = -7.0; 95% CI, -12.6 to -1.3;

conclusionsCBT for nightmares is feasible and may be efficacious for treating nightmares and comorbid insomnia for patients with persecutory delusions. It shows promise on paranoia but potentially not on suicidal ideation.

Indexed as

DreamsOutcome and Process Assessment, Health CareAdultCognitive Behavioral TherapyFeasibility StudiesFemaleHumansMaleMiddle AgedParasomniasPilot ProjectsSchizophrenia, ParanoidSingle-Blind Methodmental imagerynightmaresparanoiapsychosisschizophreniasleep

Identifiers

PMID31129983
PMCPMC6783669
OpenAlexW2947463659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.