ArticleClinical oral investigations2020
Comparison of serum lipid parameters between patients with classic cutaneous lichen planus and oral lichen planus.
Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Association of Sleep Quality, Nutritional Factors, and Salivary Melatonin and Cortisol Levels with Oral Lichen Planus: A Case-Control Study.Biomedicines · 2026Article
- Inflammatory Markers and Dyslipidemia in Patients with Oral Lichen Planus: A Case-Control Study.Diagnostics (Basel, Switzerland) · 2025Article
- Study on the potential links between clinical features of oral lichenoid mucositis and systemic diseases.BMC oral health · 2025Article
- Association Between Dyslipidemia and Lichen Planus: A Cross-Sectional Study in a Tertiary Care Hospital.Cureus · 2025Article
- Relationship between Oral Lichen Planus and Cardiovascular Disease of Atherosclerotic Origin: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Potential implication of serum lipid levels as predictive indicators for monitoring oral lichen planus.Journal of dental sciences · 2024Article
- Potential relationship of dyslipidemia with dietary patterns in oral lichen planus patients-A case-control study.Journal of dental sciences · 2023Article
- Lipid Aberrations in Lichen Planus.Metabolites · 2022Review
- Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus.Dentistry journal · 2022Article
- Increased Level of Serum Wingless-Type Mouse Mammary Tumor Virus Integration Site Family Member 5a in Patients with Cutaneous Lichen Planus.Journal of inflammation research · 2022Article
- High serum level of interleukin-6 is linked with dyslipidemia in oral lichen planus.Experimental and therapeutic medicine · 2021Article
- Oral Lichen Planus: An Updated Review of Etiopathogenesis, Clinical Presentation, and Management.Indian dermatology online journalReview
- Evaluation of the Altered Tissue Expression ofIndian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPrevious studies have shown that patients with lichen planus (LP) have an increased occurrence of inflammation-related dyslipidemia. Although classic cutaneous LP (CCLP) and oral LP (OLP) are basically known as the different subtypes of the same disease sharing the common histopathological features, they actually have significant differences both in the clinical behavior and in the molecular inflammatory pathogenesis. We aimed to compare the lipid profile of patients with CCLP and OLP. MATERIALS AND
methodsThis study included 120 patients, 30 with isolated CCLP, 30 with isolated OLP, 30 with CCLP + OLP, and 30 controls consecutively admitted to the outpatient clinics of Dermatology Department of Dokuz Eylul University Hospital, Izmir, Turkey.
resultsTriglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) values, TC/high-density lipoprotein cholesterol (HDL-C), and LDL-C/HDL-C atherogenic indexes were significantly higher, and HDL-C values were significantly lower in all LP subtypes compared with the controls. Among LP subtypes, although the differences were not statistically significant, TG, TC, and LDL-C values were markedly higher in OLP and OLP + CCLP patients compared with CCLP patients. OLP and CCLP + OLP patients also showed significantly higher TC/HDL-C and LDL-C/HDL-C atherogenic indexes compared with CCLP patients.
conclusionsPatients with OLP have a more impaired lipid metabolism and significantly higher atherogenic indexes compared with patients with CCLP. The differences in the molecular inflammatory pathways between OLP and CCLP and the longer disease duration of OLP leading to long-lasting inflammation may elucidate this distinction. CLINICAL RELEVANCE: We recommend to pay close attention to the early recognition of coexisting atherogenic dyslipidemia and to apply the early protective measures against the development of cardiovascular disease in OLP patients.
Indexed as
Identifiers
31129877What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.