Evidence map›Paper›PMID 31129810›Full record

ArticleMolecular neurobiology2019

Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus.

Sang-Gyun Kang, Charles E Mays, Nathalie Daude, Jing Yang, Satyabrata Kar, David Westaway

Open access · hybridAbstract read
In one paragraph

Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sang-Gyun KangCentre for Prions and Protein Folding Diseases, University of Alberta, 204 Brain and Aging Research Building, Edmonton, Alberta, T6G 2M8, Canada.
Charles E MaysCentre for Prions and Protein Folding Diseases, University of Alberta, 204 Brain and Aging Research Building, Edmonton, Alberta, T6G 2M8, Canada.
Nathalie DaudeCentre for Prions and Protein Folding Diseases, University of Alberta, 204 Brain and Aging Research Building, Edmonton, Alberta, T6G 2M8, Canada.
Jing YangCentre for Prions and Protein Folding Diseases, University of Alberta, 204 Brain and Aging Research Building, Edmonton, Alberta, T6G 2M8, Canada.
Satyabrata KarCentre for Prions and Protein Folding Diseases, University of Alberta, 204 Brain and Aging Research Building, Edmonton, Alberta, T6G 2M8, Canada.
David WestawayCentre for Prions and Protein Folding Diseases, University of Alberta, 204 Brain and Aging Research Building, Edmonton, Alberta, T6G 2M8, Canada. david.westaway@ualberta.ca.ORCID http://orcid.org/0000-0003-1928-4616
University of Alberta · CA

Funding

Canada Research Chairs Tier 1CIHR CIHR; MOP137094
6 · The paper itself

Abstract

The Shadoo protein (Sho) exhibits homology to the hydrophobic region of the cellular isoform of prion protein (PrP

Indexed as

AcetylcysteineAnimalsAutophagyCell Line, TumorCell NucleusGPI-Linked ProteinsHumansLeupeptinsMice, KnockoutModels, BiologicalNerve Tissue ProteinsNeurogliaNeuronsPrionsPromoter Regions, GeneticProteasome InhibitorsAcetylcysteinebenzyloxycarbonylleucyl-leucyl-leucine aldehydeGPI-Linked ProteinslactacystinLeupeptinsNerve Tissue ProteinsPrionsProteasome InhibitorsSprn protein, mouseImpaired ER importNeurons and gliaNuclear localizationProteasomal inhibitionProteostasis

Identifiers

PMID31129810
PMCPMC6815274
OpenAlexW2946735581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.