Evidence map›Paper›PMID 31129780›Full record

ArticlePurinergic signalling2019

P2X

Marianne Skals, Anne-Sofie Greve, Steen K Fagerberg, Nanna Johnsen, Mette G Christensen, Helle A Praetorius

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Purinergic signalling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. The P2X1 receptor as a therapeutic target.Purinergic signalling · 2022
    Review
  2. Review
  3. Article
  4. Article
  5. Virulence and Pathogenicity Properties ofPathogens (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marianne SkalsDepartment of Biomedicine, Aarhus University, Ole Worms Alle 4, build 1160, 8000, Aarhus C, Denmark. hp@biomed.au.dk.
Anne-Sofie GreveDepartment of Biomedicine, Aarhus University, Ole Worms Alle 4, build 1160, 8000, Aarhus C, Denmark.
Steen K FagerbergDepartment of Biomedicine, Aarhus University, Ole Worms Alle 4, build 1160, 8000, Aarhus C, Denmark.
Nanna JohnsenDepartment of Biomedicine, Aarhus University, Ole Worms Alle 4, build 1160, 8000, Aarhus C, Denmark.
Mette G ChristensenDepartment of Biomedicine, Aarhus University, Ole Worms Alle 4, build 1160, 8000, Aarhus C, Denmark.
Helle A PraetoriusDepartment of Biomedicine, Aarhus University, Ole Worms Alle 4, build 1160, 8000, Aarhus C, Denmark.ORCID 0000-0002-0970-5061
Aarhus University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urosepsis is a severe condition often caused by Escherichia coli that spontaneously have ascended the urinary tract to the kidneys causing pyelonephritis and potentially bacteraemia. The number of sepsis cases has been steadily increasing over the last decades, and there are still no specific, molecular supportive therapies for sepsis to supplement antibiotic treatment. P2X

Indexed as

Escherichia coli InfectionsReceptors, Purinergic P2X1SepsisUrinary Tract InfectionsAnimalsBenzenesulfonatesBlood PlateletsHemolysin ProteinsMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutPurinergic P2X Receptor AntagonistsPyelonephritisSuramin4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate)BenzenesulfonatesHemolysin ProteinsNF 279Purinergic P2X Receptor AntagonistsReceptors, Purinergic P2X1SuraminAntagonistE. coliP2X1SepsisThrombocytes

Identifiers

PMID31129780
PMCPMC6635539
OpenAlexW2945460632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.