Evidence map›Paper›PMID 31129699›Full record

ArticlePediatric radiology2019

Magnetic-resonance-guided focused ultrasound treatment of non-spinal osteoid osteoma in children: multicentre experience.

Francesco Arrigoni, Alessandro Napoli, Alberto Bazzocchi, Luigi Zugaro, Roberto Scipione, Federico Bruno, Pierpaolo Palumbo, Michele Anzidei, Daniele Mercatelli, Giovanni Luca Gravina and 5 more

Abstract read
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In one paragraph

Article in Pediatric radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Tumor ablation in children.Pediatric radiology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. A review of the development of histotripsy for extremity tumor ablation with a canine comparative oncology model to inform human treatments.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2023
    Review
  12. Article
  13. CIRSE Standards of Practice on Thermal Ablation of Bone Tumours.Cardiovascular and interventional radiology · 2022
    Article
  14. Article
  15. Article
  16. Benign Bone Tumors: An Overview of What We Know Today.Journal of clinical medicine · 2022
    Review
  17. Review
  18. Review
  19. Osteoid osteoma: which is the best mininvasive treatment option?European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Francesco ArrigoniDepartment of Emergency Radiology, San Salvatore Hospital, via Vetoio, 67100, L'Aquila, Italy. arrigoni.francesco@gmail.com.ORCID 0000-0001-7793-1872
Alessandro NapoliDepartment of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy.
Alberto BazzocchiDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Via G. C. Pupilli 1, 40136, Bologna, Italy.
Luigi ZugaroDepartment of Emergency Radiology, San Salvatore Hospital, via Vetoio, 67100, L'Aquila, Italy.
Roberto ScipioneDepartment of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy.
Federico BrunoDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila Via Giovanni Di Vincenzo, L'Aquila, Italy.
Pierpaolo PalumboDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila Via Giovanni Di Vincenzo, L'Aquila, Italy.
Michele AnzideiDepartment of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy.
Daniele MercatelliDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Via G. C. Pupilli 1, 40136, Bologna, Italy.
Giovanni Luca GravinaDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila Via Giovanni Di Vincenzo, L'Aquila, Italy.
Carmine ZoccaliOncological Orthopedics Department, Regina Elena National Cancer Institute, Rome, Italy.
Pejman GhanouniDepartment of Radiology, Stanford University Medical Center, Stanford, CA, USA.
Antonio BarileDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila Via Giovanni Di Vincenzo, L'Aquila, Italy.
Carlo CatalanoDepartment of Radiologic, Oncologic and Pathologic Sciences, La Sapienza University of Rome, Rome, Italy.
Carlo MasciocchiDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila Via Giovanni Di Vincenzo, L'Aquila, Italy.
University of L'Aquila · ITSapienza University of Rome · ITIstituto Ortopedico Rizzoli · ITSan Salvatore Hospital · ITStanford Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoid osteoma is a benign and painful musculoskeletal tumour that usually affects children. Current standard treatment is CT-guided radiofrequency ablation, a minimally invasive percutaneous procedure, with clinical success rates ranging between 85% and 98%. Though minimally invasive, however, this type of procedure is not free from complications.

objectiveTo investigate the efficacy and safety of magnetic resonance (MR)-guided focused ultrasound (MRgFUS), a needleless procedure of thermal ablation employed in the treatment of non-spinal osteoid osteoma in paediatric patients. MATERIALS AND

methodsWe report the results of 33 procedures of ablation of osteoid osteoma performed with MRgFUS in three university hospitals. To ablate a lesion on the bone surface, MRgFUS employs the ultrasound energy transduced along the soft tissue. The follow-up studies lasted 24 months and were performed combining clinical and imaging data.

resultsMean age of the children was 13.8 years. The clinical outcome showed a primary success of 97%. One case alone was submitted to repeat treatment because the first one failed (secondary success). No major or minor complications were recorded. During the investigation time, no relapse of symptomatology or delayed complications were observed.

conclusionAlthough our study is preliminary and limited by a low number of patients, our data show that MRgFUS is effective. This suggests that it might be useful as the first-line treatment in paediatric patients with osteoid osteoma.

Indexed as

High-Intensity Focused Ultrasound AblationMagnetic Resonance Imaging, InterventionalAdolescentBone NeoplasmsChildFemaleHumansMaleOsteoma, OsteoidAdolescentsBoneChildrenMagnetic-resonance-guided focused ultrasoundOsteoid osteoma

Identifiers

PMID31129699
OpenAlexW2945827723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.