Trial reportPediatric research2019
Maternal anemia type during pregnancy is associated with anemia risk among offspring during infancy.
Trial report in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- A systematic review and meta-analysis of the prevalence and associated factors of iron-deficiency anemia among Chinese children under 6 years of age.Frontiers in pediatrics · 2025Pooled it
- Maternal Iron Status in Pregnancy and Child Health Outcomes after Birth: A Systematic Review and Meta-Analysis.Nutrients · 2021Pooled it
- Trial
- The effect of iron supplementation on maternal iron deficiency anemia does not differ by baseline anemia type among Tanzanian pregnant women without severe iron deficiency anemia.European journal of nutrition · 2023Trial
- The hidden vulnerability: heavy and persistent burden of dietary iron deficiency among women and children in China, India and globally based on the global burden of disease 2021.Annals of medicine · 2026Article
- Multidimensional Profiles Associated with Gestational Anemia in Primary Healthcare Networks of Northern Peru.Healthcare (Basel, Switzerland) · 2026Article
- Areca Nut Chewing as a Modifiable Risk Factor for Maternal Anemia, Prematurity and Fetal Low Birth Weight: A Cross Sectional Study in Teluk Wondama, West Papua.International journal of women's health · 2026Article
- The Association of Infant Birth Sizes and Anemia under Five Years Old: A Population-Based Prospective Cohort Study in China.Nutrients · 2024Article
- Exploring the Link between Maternal Hematological Disorders during Pregnancy and Neurological Development in Newborns: Mixed Cohort Study.Life (Basel, Switzerland) · 2023Article
- Elevated first-trimester hepcidin level is associated with reduced risk of iron deficiency anemia in late pregnancy: a prospective cohort study.Frontiers in nutrition · 2023Article
- Child anemia in Cambodia: A descriptive analysis of temporal and geospatial trends and logistic regression-based examination of factors associated with anemia in children.PLOS global public health · 2023Article
- Maternal hemoglobin concentrations across pregnancy and child health and development from birth through 6-7 years.Frontiers in nutrition · 2023Article
- Identification of Serum Ferritin-Specific Nanobodies and Development towards a Diagnostic Immunoassay.Biomolecules · 2022Article
- Impact of Crohn's disease during pregnancy on children with attention deficit hyperactivity disorder: A review.Annals of medicine and surgery (2012) · 2022Review
- Magnitude of Anemia and Its Associated Factors Among Pregnant Women Attending Antenatal Care in Hiwot Fana Specialized University Hospital in Eastern Ethiopia.Frontiers in public health · 2022Article
- Article
- Maternal health status and household food security on determining childhood anemia in Bangladesh -a nationwide cross-sectional study.BMC public health · 2021Article
- Infantile Iron Deficiency Affects Brain Development in Monkeys Even After Treatment of Anemia.Frontiers in human neuroscience · 2021Article
- Iron Deficiency and Iron Deficiency Anemia: Implications and Impact in Pregnancy, Fetal Development, and Early Childhood Parameters.Nutrients · 2020Review
- Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundWe evaluated the association between etiology of maternal anemia and iron status throughout infancy.
methodsSamples from a study designed to examine Praziquantel treatment during pregnancy were used (n = 359). All women were infected with schistosomiasis and randomized to Praziquantel or placebo at 16 ± 2 weeks' gestation. Hemoglobin, serum ferritin (SF), soluble transferrin receptor (sTfR), hepcidin, C-reactive protein, and interleukin-6 were measured in maternal and infant blood. The relationship between both maternal Praziquantel treatment and etiology of anemia and infant iron status was evaluated.
resultsMaternal iron-deficiency anemia was associated with increased risk of infant anemia at 6 months of age. Infants of mothers with the lowest levels of circulating hepcidin during gestation, likely a marker for iron deficiency, had higher sTfR:SF levels and lower hemoglobin levels, particularly at 12 months of age. Maternal non-iron-deficiency anemia (NIDA) did not impact infant anemia risk or iron status. Maternal treatment for schistosomiasis had no effect on infant hematologic status.
conclusionsMaternal iron deficiency anemia was associated with an increased risk for anemia or iron deficiency during late infancy. We did not observe an association between maternal NIDA and increased risk for iron deficiency during infancy.
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