SynthesisAmerican journal of nephrology2019
The Prevalence of Intradialytic Hypotension in Patients on Conventional Hemodialysis: A Systematic Review with Meta-Analysis.
Synthesis in American journal of nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05052151 (Hemodynamic Effects of Low vs. High Dialysate Temperature or Bicarbonate Concentration in Chronic Hemodialysis Patients), which is not on this map. Cited by 73 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hemodynamic Effects of Low vs. High Dialysate Temperature or Bicarbonate Concentration in Chronic Hemodialysis Patients
Who cites it
73 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prediction of intradialytic hypotension by machine learning: A systematic review.Journal of nephrology · 2025Pooled it
- Effects of diuretics on intradialytic hypotension in maintenance dialysis patients: a systematic review and meta-analysis.International urology and nephrology · 2021Pooled it
- Identification of intradialytic hemodynamic phenotypes using latent profile analysis.Clinical kidney journal · 2026Article
- Review
- Potential implications of subclinical hypervolemia, identified by a multiparametric approach, in causing left ventricular hypertrophy in clinically euvolemic children on dialysis: a prospective longitudinal pilot study.Pediatric nephrology (Berlin, Germany) · 2026Article
- MI-Net: a dual-stream feature network based on Mamba-convolutional neural network (CNN) fusion to predict intradialytic hypotension using multimodal data.Quantitative imaging in medicine and surgery · 2026Article
- The value of pleth variability index in predicting hypotension during maintenance hemodialysis: a prospective observational multicenter study (PVi-HD study).BMC nephrology · 2026Observational
- Accurate prediction of intradialytic hypo- and hypertension in haemodialysis patients: the dual-attention Transformer model.Clinical kidney journal · 2026Article
- Continuous monitoring of relative blood volume allows real-time assessment of intradialytic hypotension risk.Clinical kidney journal · 2026Article
- The Effects of Sertraline on Dialysis-Induced Hypotension: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Intradialytic Hypotensive Episodes are Only Occasionally Associated With Adverse Symptoms.Kidney international reports · 2026Article
- Machine learning model for predicting hypotension following continuous renal replacement therapy initiation in end-stage kidney disease patients: a SHAP-interpretable approach.Frontiers in medicine · 2026Article
- Intradialytic hypotension is severely underreported by intermittent blood pressure readings.Clinical kidney journal · 2026Article
- Intra-Session recurrence in intradialytic hypotension prediction: evaluation implications and recurrence-aware modeling.Frontiers in digital health · 2026Article
- Comparative effects of 1.25 vs. 1.5 mmol/L dialysate calcium concentrations on blood pressure variability during hemodialysis: a two-center retrospective study.Frontiers in medicine · 2026Article
- Updates in the management of intradialytic hypotension: Emerging strategies and innovations.World journal of nephrology · 2025Review
- Prevalence and associated factors of intradialytic hypotension among patients with kidney failure on maintenance hemodialysis at Kiruddu National Referral Hospital, Uganda.BMC nephrology · 2025Article
- Prediction of intradialytic hypotension based on heart rate variability and skin sympathetic nerve activity using LASSO-enabled feature selection: a two-center study.Renal failure · 2025Article
- Occurrence of benzodiazepines and nonbenzodiazepines usage among newly-onset of peritoneal dialysis versus hemodialysis patients.BMC nephrology · 2025Article
- The Effect of Dialysate Sodium on Endothelial Injury and Microcirculatory Dysfunction.Kidney360 · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntradialytic hypotension (IDH) is considered to be a frequent complication of hemodialysis (HD) and is associated with symptom burden, increased incidence of access failure, cardiovascular events, and higher mortality. This systematic literature review aims to analyse studies that investigated the prevalence of IDH. A complicating factor herein is that many different definitions of IDH are used in literature.
methodsA systematic literature search from databases, Medline, Cinahl, EMBASE, and the Cochrane library to identify studies reporting on the actual prevalence of IDH was conducted. Studies were categorized by the type of definition used for the prevalence of IDH. A meta-analysis of the prevalence of IDH was performed.
resultsIn a meta-analysis comprising 4 studies including 1,694 patients and 4 studies including 13,189 patients, the prevalence of HD sessions complicated by IDH was 10.1 and 11.6% for the European Best Practice Guideline (EBPG) definition and the Nadir <90 definition, respectively. The proportion of patients with frequent IDH could not reliably be established because of the wide range in cutoff values that were used to identify patients with frequent IDH. There was a large variety in the prevalence of symptoms and interventions. Major risk factors associated with IDH across studies were diabetes, a higher interdialytic weight gain, female gender, and lower body weight.
conclusionOur meta-analysis suggests that the prevalence of IDH is lower than 12% for both the EBPG and the Nadir <90 definition which is much lower than stated in most reviews.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.