ArticleBMJ open2019
Challenges and barriers to optimising sedation in intensive care: a qualitative study in eight Scottish intensive care units.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01634451 (Development and Evaluation of Strategies to Improve Sedation Quality in InTensive Care), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development and Evaluation of Strategies to Improve Sedation Quality in InTensive Care
Who cites it
10 citing papers in PubMed, 33 citations in OpenAlex.
- Alpha2 agonists for sedation to produce better outcomes for adults with critical illness: a synopsis of the A2B RCT with cost-effectiveness and process evaluation.Health technology assessment (Winchester, England) · 2026Trial
- Enhancing patient safety: factors influencing critical care nurses' intravenous sedation practices in mechanically ventilated patients.BMC nursing · 2026Article
- Accuracy and Documentation of Richmond Agitation-Sedation Scale Assessments in a Cardiothoracic Critical Care Unit: A Prospective, Cross-Sectional Audit.Nursing in critical care · 2026Article
- Optimising pain management in intensive care setting: Insights from a realist evaluation.International journal of nursing studies advances · 2026Review
- Development and Psychometric Testing of the Optimizing Context in Assessing Sedation in ICU (OCEAN-ICU) Instrument to Optimize Sedation Use in Intensive Care.Critical care explorations · 2026Article
- Review
- Anesthesiology and critical care medicine as "text": the power of qualitative research in a world of physiology, pharmacology, and fibrillation.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Article
- Article
- Sedation in the Intensive Care Unit.Current anesthesiology reports · 2021Review
- The effects of sedation cessation within the first four hours of intensive care unit admission in mechanically ventilated critically ill patients - a quality improvement study.EClinicalMedicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesVarious strategies to promote light sedation are highly recommended in recent guidelines, as deep sedation is associated with suboptimum patient outcomes. Yet, the challenges met by clinicians in delivering high-quality analgosedation is rarely addressed. As part of the evaluation of a cluster-randomised quality improvement trial in eight Scottish intensive care units (ICUs), we aimed to understand the challenges to optimising sedation in the Scottish ICU settings prior to the trial. This article reports on the findings.
designA qualitative exploratory design: We conducted focus groups (FG) with clinicians during the preintervention period.
resultsThree themes emerged from the inductive analysis: (a) a recent shift in sedation practice, (b) uncertainty in decision-making and (c) system-level factors including the ICU environment, organisational factors and educational gaps. Clinicians were challenged daily to manage agitated or difficult-to-sedate patients in the era of a progressive mantra of 'just sedate less' imposed by the pain-agitation-delirium guidelines.
conclusionsThe current implementation of guidelines does not support behaviour change strategies to allow a patient-focused approach to sedation management, which obstructs optimum sedation-analgesia management. Recognition of the various challenges when mandating less sedation needs to be considered and novel sedation-analgesia strategies should allow a system-level approach to improve sedation-analgesia quality. DESIST REGISTRATION NUMBER: NCT01634451.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.