Evidence map›Paper›PMID 31129571›Full record

SynthesisBMJ open2019

Herbal medications for anxiety, depression, pain, nausea and vomiting related to preoperative surgical patients: a systematic review and meta-analysis of randomised controlled trials.

Ana Paula Nappi Arruda, Yuchen Zhang, Huda Gomaa, Cristiane de Cássia Bergamaschi, Caio Chaves Guimaraes, Leonardo A R Righesso, Mariana Del Grossi Paglia, Silvio Barberato-Filho, Luciane Cruz Lopes, Ana Patricia Ayala Melendez and 4 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Ana Paula Nappi ArrudaDepartment of Surgery and Orthopedics, UNESP - Universidade Estadual Paulista, Faculty of Medicine, Botucatu, São Paulo, Brazil.
Yuchen ZhangFaculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Huda GomaaDepartment of Pharmacy, Tanta Chest Hospital, Tanta, Egypt.
Cristiane de Cássia BergamaschiPharmaceutical Sciences, University of Sorocaba, Sorocaba, São Paulo, Brazil.
Caio Chaves GuimaraesTerapeutica, Faculdade Sao Leopoldo Mandic, Campinas, Brazil.
Leonardo A R RighessoOral & Maxillofacial Surgery, University Medical Center Mainz, Mainz, Germany.
Mariana Del Grossi PagliaPharmaceutical Sciences, University of Sorocaba, Sorocaba, São Paulo, Brazil.
Silvio Barberato-FilhoPharmaceutical Sciences, University of Sorocaba, Sorocaba, São Paulo, Brazil.
Luciane Cruz LopesPharmaceutical Sciences, University of Sorocaba, Sorocaba, São Paulo, Brazil.
Ana Patricia Ayala MelendezGerstein Science Information Centre, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-3613-2270
Luciane Dias de OliveiraDepartment of Biosciences and Oral Diagnosis, UNESP - Universidade Estadual Paulista, Institute of Science and Technology, São José dos Campos, Brazil.
Lucas Paula-RamosDepartment of Biosciences and Oral Diagnosis, UNESP - Universidade Estadual Paulista, Institute of Science and Technology, São José dos Campos, Brazil.
Bradley JohnstonCommunity Health and Epidemiology, Dalhousie University Faculty of Medicine, Halifax, Nova Scotia, Canada.
Regina El DibDepartment of Biosciences and Oral Diagnosis, UNESP - Universidade Estadual Paulista, Institute of Science and Technology, São José dos Campos, Brazil.
Universidade de Sorocaba · BRUniversidade Estadual Paulista (Unesp) · BRUniversity of Toronto · CADalhousie University · CAFaculdade São Leopoldo Mandic · BRJohannes Gutenberg University Mainz · DESt. Joseph’s Healthcare Hamilton · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo summarise the effects of herbal medications for the prevention of anxiety, depression, pain, and postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic, obstetrical/gynaecological or cardiovascular surgical procedures.

methodsSearches of MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials and LILACS up until January 2018 were performed to identify randomised controlled trials (RCTs). We included RCTs or quasi-RCTs evaluating any herbal medication among adults undergoing laparoscopic, obstetrical/gynaecological or cardiovascular surgeries. The primary outcomes were anxiety, depression, pain and PONV. We used the Grading of Recommendations Assessment, Development and Evaluation approach to rate overall certainty of the evidence for each outcome.

resultsEleven trials including 693 patients were eligible. Results from three RCTs suggested a statistically significant reduction in vomiting (relative risk/risk ratio (RR) 0.57; 95% CI 0.38 to 0.86) and nausea (RR 0.69; 95% CI 0.50 to 0.96) with the use of

conclusionsThere is very low-certainty evidence regarding the efficacy of both PROSPERO REGISTRATION NUMBER: CRD42016042838.

Indexed as

PhytotherapyRandomized Controlled Trials as TopicAnxietyDepressionHumansPainPlant PreparationsPostoperative Nausea and VomitingPreoperative CarePlant Preparationscardiovascular surgeryGRADEgynecologic surgeryherbal, laparoscopyobstetrical surgerysystematic review

Identifiers

PMID31129571
PMCPMC6538060
OpenAlexW2946126140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.