ArticleDevelopmental cognitive neuroscience2019
Alterations of structural and functional connectivity in profound sensorineural hearing loss infants within an early sensitive period: A combined DTI and fMRI study.
Article in Developmental cognitive neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Hearing loss and dementia: radiologic and biomolecular basis of their shared characteristics. A systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- Hierarchical Network Adaptations and Structure-Function Scaffolding in the Deaf Adult Brain.Brain topography · 2026Article
- Alterations of White Matter Structural Brain Network in Children With Sensorineural Hearing Loss: A Graph Theory Analysis for Auditory Sensitivity Period.Neural plasticity · 2026Article
- Functional Changes in the Glymphatic System in Children With Sensorineural Hearing Loss: A Study of Diffusion Tensor Imaging.Neural plasticity · 2026Article
- Assessment of resting state structural-functional relationships in perisylvian region during the early weeks after birth.Brain structure & function · 2025Article
- Developmental alterations in brain network asymmetry in 3- to 9-month infants with congenital sensorineural hearing loss.Science advances · 2025Article
- Altricial brains and the evolution of infant vocal learning.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Direct recording of electrically evoked cortical potentials from cochlear implants demonstrates feasibility and clinical relevance in pediatric users.Scientific reports · 2025Article
- Aberrant static and dynamic functional network connectivity in patients with noise-induced hearing loss.Quantitative imaging in medicine and surgery · 2025Article
- Article
- The neural characteristics influencing literacy outcome in children with cochlear implants.Brain communications · 2025Article
- Brain networks in newborns and infants with and without sensorineural hearing loss: A functional near-infrared spectroscopy study.World journal of psychiatry · 2024Article
- Dynamic functional network connectivity in children with profound bilateral congenital sensorineural hearing loss.Pediatric radiology · 2024Article
- Language networks of normal-hearing infants exhibit topological differences between resting and steady states: An fNIRS functional connectivity study.Human brain mapping · 2024Article
- Alterations of the cerebral microstructure in patients with noise-induced hearing loss: A diffusion tensor imaging study.Brain and behavior · 2024Article
- Motor Processing in Children With Cochlear Implants as Assessed by Functional Near-Infrared Spectroscopy.Perceptual and motor skills · 2024Article
- Cerebral cortex functional reorganization in preschool children with congenital sensorineural hearing loss: a resting-state fMRI study.Frontiers in neurology · 2024Article
- Functional reorganization of intranetwork and internetwork connectivity in patients with Ménière's disease.Scientific reports · 2023Article
- Article
- Effect of Sound Coding Strategies on Music Perception with a Cochlear Implant.Journal of clinical medicine · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to heightened level of neuroplasticity, there is a sensitive period (2-4 years after birth) that exists for optimal central auditory development. Using diffusion tensor imaging combined with resting-state functional connectivity (rsFC) analysis, this study directly investigates the structural connectivity alterations of the whole brain white matter (WM) and the functional reorganization of the auditory network in infants with sensorineural hearing loss (SNHL) during the early sensitive period. 46 bilateral profound SNHL infants prior to cochlear implantation (mean age, 17.59 months) and 33 healthy controls (mean age, 18.55 months) were included in the analysis. Compared with controls, SNHL infants showed widespread WM alterations, including bilateral superior longitudinal fasciculus, inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, right corticospinal tract, posterior thalamic radiation and left uncinate fasciculus. Moreover, SNHL infants demonstrated increased rsFC between left/right primary auditory cortex seeds and right insula and superior temporal gyrus. In conclusion, this study suggests that SNHL in the early sensitive period is associated with diffuse WM alterations that mainly affect the auditory and language pathways. Furthermore, increased rsFC in areas mainly associated with auditory and language networks may potentially reflect reorganization and compensatory activation in response to auditory deprivation during the early sensitive period.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.