Evidence map›Paper›PMID 31129370›Full record

ArticleContemporary clinical trials2019

Optimizing the use of continuous glucose monitoring in young children with type 1 diabetes with an adaptive study design and multiple randomizations.

Cari Berget, Kimberly A Driscoll, Ann Lagges, Samantha Lange, Linda A DiMeglio, Tamara S Hannon, Stephanie E Woerner, Esti Iturralde, Regan C Barley, Sarah Hanes and 3 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Cari BergetUniversity of Colorado Denver, School of Medicine, Barbara Davis Center for Childhood Diabetes, United States of America.
Kimberly A DriscollUniversity of Colorado Denver, School of Medicine, Barbara Davis Center for Childhood Diabetes, United States of America.
Ann LaggesIndiana University, School of Medicine, Clinical Psychiatry, United States of America.
Samantha LangeUniversity of Colorado Denver, School of Medicine, Barbara Davis Center for Childhood Diabetes, United States of America.
Linda A DiMeglioIndiana University, School of Medicine, Pediatric Endocrinology/Diabetology, United States of America.
Tamara S HannonIndiana University, School of Medicine, Pediatric Endocrinology/Diabetology, United States of America.
Stephanie E WoernerIndiana University, School of Medicine, Pediatric Endocrinology/Diabetology, United States of America.
Esti IturraldeStanford University, School of Medicine, Pediatric Diabetes & Endocrinology, United States of America; Kaiser Permanente Norther California, Division of Research, United States of America.
Regan C BarleyStanford University, School of Medicine, Pediatric Diabetes & Endocrinology, United States of America.
Sarah HanesStanford University, School of Medicine, Pediatric Diabetes & Endocrinology, United States of America.
Korey K HoodStanford University, School of Medicine, Pediatric Diabetes & Endocrinology, United States of America. Electronic address: kkhood@stanford.edu.
Bruce B BuckinghamStanford University, School of Medicine, Pediatric Diabetes & Endocrinology, United States of America.
Toddler Diabetes Technology Study Group

Funding

Training Program in Diabetes ResearchT32DK063687 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Andrea Steck · 2002 to 2026
$5.2M
Using a Closed-Loop System Plus Behavioral Supports in Preschoolers with DiabetesDP3DK104059 · NIDDK · STANFORD UNIVERSITY · PI BUCKINGHAM, BRUCE A, DIMEGLIO, LINDA A · 2014 to 2014
$2.1M
NIDDK NIH HHS DP3 DK104059NIDDK NIH HHS T32 DK063687
6 · The paper itself

Abstract

Parents of young children with type 1 diabetes (T1D) experience unique, developmental challenges in managing their child's T1D, resulting in psychosocial distress. Only a small portion of young children reach glucose goals and adherence to diabetes devices that help improve T1D management have historically been low in this population. The purpose of this study is to test four interventions that couple developmentally tailored behavioral supports with education to optimize use of diabetes devices, improve glucose control, and reduce psychosocial distress for parents of young children with T1D. The study team designed four behavioral interventions, two aimed at improving glucose control and two aimed at optimizing use of diabetes devices. The goal of this paper is to describe the behavioral interventions developed for this study, including the results of a pilot test, and describe the methods and analysis plan to test this intervention strategy with ninety participants in a large-scale, randomized trial using a sequential multiple assignment randomization trial (SMART) design. A SMART design will permit a clinically relevant evaluation of the intervention strategy, as it allows multiple randomizations based on individualized assessments throughout the study instead of a fixed intervention dose seen in most traditional randomized controlled trials.

Indexed as

AdultBlood GlucoseBlood Glucose Self-MonitoringChild, PreschoolDiabetes Mellitus, Type 1HumansInfantParentsPatient CompliancePatient Education as TopicRandomized Controlled Trials as TopicSurveys and QuestionnairesBlood Glucose

Identifiers

PMID31129370
PMCPMC8082673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.