ArticleMedical dosimetry : official journal of the American Association of Medical Dosimetrists
Postmastectomy radiotherapy for left-sided breast cancer patients: Comparison of advanced techniques.
Article in Medical dosimetry : official journal of the American Association of Medical Dosimetrists. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Comparative dosimetric and radiobiological assessment of a hybrid-VMAT strategy incorporating supplemental short-arcs for left-sided postmastectomy radiotherapy.Frontiers in oncology · 2026Article
- Clinical implementation of a hybrid solitary dynamic portal radiotherapy for left-sided post-mastectomy chest-wall and regional nodal irradiation using Monaco TPS.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Article
- Post-mastectomy radiotherapy: Impact of bolus thickness and irradiation technique on skin dose.Zeitschrift fur medizinische Physik · 2024Article
- Minimizing normal tissue low dose bath for left breast Volumetric Modulated Arc Therapy (VMAT) using jaw offset.Journal of applied clinical medical physics · 2024Article
- A dosiomics model for prediction of radiation-induced acute skin toxicity in breast cancer patients: machine learning-based study for a closed bore linac.European journal of medical research · 2024Article
- Impact of Dose Calculation Algorithms and Radiobiological Parameters on Prediction of Cardiopulmonary Complications in Left Breast Radiation Therapy.Journal of biomedical physics & engineering · 2024Article
- Evaluation of conventional IMRT and VMAT strategies for postmastectomy radiation therapy after immediate implant-based reconstruction using the new ESTRO-ACROP contouring guidelines.Radiation and environmental biophysics · 2024Article
- Dosimetric analysis of half-field-based VMAT with the deep inspiration breath-hold technique for left breast cancer patients following breast-conserving surgery.Frontiers in oncology · 2024Article
- Comparative dosimetric and radiobiological assessment of left-sided whole breast and regional nodes with advanced radiotherapy techniques.Journal of radiation research · 2023Article
- A dose planning study for cardiac and lung dose sparing techniques in left breast cancer radiotherapy: Can free breathing helical tomotherapy be considered as an alternative for deep inspiration breath hold?Technical innovations & patient support in radiation oncology · 2023Article
- Article
- Comprehensive nodal breast VMAT: solving the low-dose wash dilemma using an iterative knowledge-based radiotherapy planning solution.Journal of medical radiation sciences · 2022Article
- Artificial Intelligence-Based Automated Treatment Planning of Postmastectomy Volumetric Modulated Arc Radiotherapy.Frontiers in oncology · 2022Article
- Non-coplanar volumetric modulated arc therapy for locoregional radiotherapy of left-sided breast cancer including internal mammary nodes.Radiology and oncology · 2021Article
- A dosimetric and radiobiological evaluation of VMAT following mastectomy for patients with left-sided breast cancer.Radiation oncology (London, England) · 2021Article
- Article
- Dosimetric Comparison of Helical Tomotherapy, Volume-Modulated Arc Therapy, and Fixed-Field Intensity-Modulated Radiation Therapy in Locally Advanced Nasopharyngeal Carcinoma.Frontiers in oncology · 2021Article
- Auxiliary Structures-Assisted Radiotherapy Improvement for Advanced Left Breast Cancer.Frontiers in oncology · 2021Article
- Cost-effectiveness analysis of advanced radiotherapy techniques for post-mastectomy breast cancer patients.Cost effectiveness and resource allocation : C/E · 2020Article
- Dosimetric and Radiobiological Comparison of Five Techniques for Postmastectomy Radiotherapy with Simultaneous Integrated Boost.BioMed research international · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Postmastectomy radiotherapy (PMRT) has been shown to improve the overall survival for invasive breast cancer patients, and many advanced radiotherapy technologies were adopted for PMRT. The purpose of our study is to compare various advanced PMRT techniques including fixed-beam intensity-modulated radiotherapy (IMRT), non-coplanar volumetric modulated arc therapy (NC-VMAT), multiple arc VMAT (MA-VMAT), and tomotherapy (TOMO). Results of standard VMAT and mixed beam therapy that were published by our group previously were also included in the plan comparisons. Treatment plans were produced for nine PMRT patients previously treated in our clinic. The plans were evaluated based on planning target volume (PTV) coverage, dose homogeneity index (DHI), conformity index (CI), dose to organs at risk (OARs), normal tissue complication probability (NTCP) of pneumonitis, lifetime attributable risk (LAR) of second cancers, and risk of coronary events (RCE). All techniques produced clinically acceptable PMRT plans. Overall, fixed-beam IMRT delivered the lowest mean dose to contralateral breast (1.56 ± 0.4 Gy) and exhibited lowest LAR (0.6 ± 0.2%) of secondary contralateral breast cancer; NC-VMAT delivered the lowest mean dose to lungs (7.5 ± 0.8 Gy), exhibited lowest LAR (5.4 ± 2.8%) of secondary lung cancer and lowest NTCP (2.1 ± 0.4%) of pneumonitis; mixed beam therapy delivered the lowest mean dose to heart (7.1 ± 1.3 Gy) and exhibited lowest RCE (8.6 ± 7.1%); TOMO plans provided the most optimal target coverage while delivering higher dose to OARs than other techniques. Both NC-VMAT and MA-VMAT exhibited lower values of all OARs evaluation metrics compare to standard VMAT. Fixed-beam IMRT, NC-VMAT, and mixed beam therapy could be the optimal radiation technique for certain breast cancer patients after mastectomy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.