Evidence map›Paper›PMID 31127837›Full record

Trial reportPain medicine (Malden, Mass.)2019

A Randomized Clinical Trial of Group Acupuncture for Painful Diabetic Neuropathy Among Diverse Safety Net Patients.

Maria T Chao, Dean Schillinger, Unity Nguyen, Trilce Santana, Rhianon Liu, Steve Gregorich, Frederick M Hecht

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pain medicine (Malden, Mass.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  4. Trial
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  7. Article
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  11. Article
  12. Review
  13. Article
  14. Effect of Acupuncture on Diabetic Neuropathy: A Narrative Review.International journal of molecular sciences · 2021
    Review
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Maria T ChaoOsher Center for Integrative Medicine.
Dean SchillingerDivision of General Internal Medicine, University of California, San Francisco, San Francisco, California, USA.
Unity NguyenOsher Center for Integrative Medicine.
Trilce SantanaOsher Center for Integrative Medicine.
Rhianon LiuOsher Center for Integrative Medicine.
Steve GregorichDivision of General Internal Medicine, University of California, San Francisco, San Francisco, California, USA.
Frederick M HechtOsher Center for Integrative Medicine.
Osher Center for Integrative MedicineUniversity of California, San Francisco · USIntegrative Medicine Institute · US

Funding

RESOURCE CENTER FOR AGING RESEARCH IN DIVERSE POPULATIONP30AG015272 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Torsten Brian Neilands · 1997 to 2026
$19.5M
Clinical and Transtional Science InstituteKL2TR000143 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$11.9M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Mentoring and Research in Integrative MedicineK24AT007827 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HECHT, FREDERICK M · 2013 to 2022
$1.8M
Group acupuncture for painful diabetic neuropathy among underserved patientsK01AT006545 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAO, MARIA T · 2011 to 2015
$720k
NCATS NIH HHS KL2 TR000143NCCIH NIH HHS K01 AT006545NCCIH NIH HHS K24 AT007827NIA NIH HHS P30 AG015272NIDDK NIH HHS P30 DK092924
6 · The paper itself

Abstract

objectiveExisting pharmacologic approaches for painful diabetic neuropathy (PDN) are limited in efficacy and have side effects. We examined the feasibility, acceptability, and effects of group acupuncture for PDN. DESIGN AND

settingWe randomized patients with PDN from a public safety net hospital to 1) usual care, 2) usual care plus 12 weeks of group acupuncture once weekly, or 3) usual care plus 12 weeks of group acupuncture twice weekly.

methodsThe primary outcome was change in weekly pain intensity (daily 0-10 numerical rating scale [NRS] averaged over seven days) from baseline to week 12. We also assessed health-related quality of life and related symptoms at baseline and weeks 6, 12, and 18.

resultsWe enrolled 40 patients with PDN (baseline pain = 5.3). Among participants randomized to acupuncture, 92% attended at least one treatment (mean treatments = 10.1). We observed no significant differences between once- vs twice-weekly acupuncture and combined those groups for the main analyses. Compared with usual care, participants randomized to acupuncture experienced greater decreases in pain during the 12-week intervention period (between-group differences from baseline = -2.06, 95% confidence interval [CI] = -3.01 to -1.10), but benefits were not maintained after acupuncture ended (baseline to week 18 = -0.61, 95% CI = -1.46 to 0.24). Quality of life improved for acupuncture participants (baseline to week 12 difference = 11.79, 95% CI = 1.92 to 21.66), but group differences were not significant compared with usual care (25.58, 95% CI = -3.90 to 55.06).

conclusionsGroup acupuncture is feasible and acceptable among linguistically and racially diverse safety net patients. Findings suggest clinically relevant reduction in pain from PDN and quality of life improvements associated with acupuncture, with no differences based on frequency.

Indexed as

Acupuncture TherapyPatient SafetyAdultDiabetes MellitusDiabetic NeuropathiesFemaleHumansMaleMiddle AgedPainQuality of LifeAcupunctureDiabetesHealth DisparitiesNeuropathyPainQuality of LifeRandomized Clinical Trial

Identifiers

PMID31127837
PMCPMC7963203
OpenAlexW2945704068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.